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Study on the immunogenicity of recombinant virus of pseudorabies- porcine Circovius Type 2-porcine parvovirus |
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Abstract The recombinant pseudorabies virus expressing ORF2 gene of porcine circovius type 2 and VP2 gene of porcine parvovirus was developed into trivalence genetically engineering vaccine to inject mice, and the result showed that the recombinant virus SA215(D)had lower virulence than velogenic strain which could resist the attack of PRV Fa strain and successfully induced humoral and cellular immune response in mice. This study established the foundation for the development of trivalence genetically engineering vaccine .
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Received: 23 October 2007
Published: 25 July 2008
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