Computational identification of microRNAs and their targets

China Biotechnology

2008, Vol. 28

Issue (10): 118-123 DOI:

Computational identification of microRNAs and their targets

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Abstract

The discovery of microRNAs (miRNAs) has introduced a new paradigm into gene regulatory systems. Since inception, computational methods have been an invaluable tool complementing experimental approaches, and many discoveries have been obtained through combination of experimental and computational approaches. In this review, we summarize the knowledge that has been accumulated about the principles of miRNAs and target recognition. The currently available computational methodologies and software for prediction of miRNA and their target genes also have been discussed.

Key words： miRNA bioinformatics miRNA target

Received: 08 June 2008 Published: 25 October 2008

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Cite this article:

. Computational identification of microRNAs and their targets. China Biotechnology, 2008, 28(10): 118-123.

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https://manu60.magtech.com.cn/biotech/ OR https://manu60.magtech.com.cn/biotech/Y2008/V28/I10/118

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