中国生物工程杂志

As the development of mechanization and transportation，there are more and more peripheral nerve wound happened. Although the damaged nerves can be bridged by an end to end surgery operation, when the damnification is very long, the surgery would loss its effect because of existing of stress between the two ends. Nerve guide conduit can provide a proper micro-environment for the self-regeneration of damaged nerve. This paper introduces the judge criterion of nerve self-regeneration, the development of nerve guide conduits materials, the effect of nerve generated factors， some preparation methods of nerve guide conduits， and on the base of foregoing researches, present the required properties of materials and structures for appropriate nerve guide conduit.