中国生物工程杂志

Objective: To study the physical and chemical attributes of nanoparticulated aluminum hydroxide adjuvant (NAHA) before and after autoclaving. Methods: Turbimetric Assay (TA), the pH and the diameter of Nanometer-Particles (NP) were applied to this comparison. Results: the pH was slightly decreased during the autoclaving, but there was no turbimetric change and diametric change of the NP. Conclusion： Nanometer-aluminium hydroxide adjuvant can be sterilized by autoclaving during the production of bacterin.