CD127 and T lymphocytes

China Biotechnology

2007, Vol. 27

Issue (5): 113-119 DOI:

CD127 and T lymphocytes

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Abstract

CD127 is the interleukin-7 receptor α (IL-7Rα), it regulates the specific respond of T lymphocytes to IL-7. CD127 plays an indispensable role in the development of thymocytes into T lymphocytes, the survival and homeostatic proliferation of memory T cells. There are only two phases of the life period of T cells that do not express CD127: immature CD4+8+double positive (DP) thymocytes and activated T cells. Recently, CD127 was found that it play an important role as the specific marker of memory T cells and regulator T cells. The role and mechanism of CD127 in the life period of T cells were discussed herein

Key words： CD127 il-17 T lymphocytes

Received: 22 January 2007 Published: 25 May 2007

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Cite this article:

. CD127 and T lymphocytes. China Biotechnology, 2007, 27(5): 113-119.

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https://manu60.magtech.com.cn/biotech/ OR https://manu60.magtech.com.cn/biotech/Y2007/V27/I5/113

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