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中国生物工程杂志

China Biotechnology
China Biotechnology
研究报告     
Prediction of secondary structure and B cell epitope for capsid protein of SVDV
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Abstract  The secondary structure of Capsid protein was predicted by the methods of Chou-Fasman, Garnier-Robson and Karplus-Schultz based on the sepuence of capsid protein gene of Swine Vesicular Disease Virus (SVDV) and hydrophilicity, surface probility plot and antigenic index for capsid protein were obtained by the methods of Kyte-Doolittle, Emini and Jameson-wolf respectively, Combining the results according to these methods, the B cell epitopes for capsid protein of SVDV were predicted. The results showed that there are much flexible region such as coil region and turn region in capsid protein of SVDV and there are more predominant B cell epitopes in VP1 than in VP2 and VP3. This study would be helpful for identification of B cell epitopes for capsid protein using experimental methods and research of reverse vaccine of SVDV.

Key wordssecondary structure      B cell epitope      Swine vesicular disease virus      capsid protein     
Received: 16 November 2005      Published: 25 May 2006
Cite this article:

. Prediction of secondary structure and B cell epitope for capsid protein of SVDV. China Biotechnology, 2006, 26(05): 1-6.

URL:

https://manu60.magtech.com.cn/biotech/     OR     https://manu60.magtech.com.cn/biotech/Y2006/V26/I05/1

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