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Abstract The expression of specific genes in sex chromosomes is the basis of sexspecific membrane protein in mammalian spermatozoa. The gene expression products are shared among spermatozoa through intercellular bridges, however, the phenomena of male transmissionratio distortion and sex ratio distortion proved that differential proteins exist between X and Y spermatozoa. In addition, the existence of sexspecific proteins was confirmed by the separation experiment of X/Y chromosome bearing spermatozoa and the detection result of sex specific proteins. At the same time, it was also confirmed that the difference of the sexspecific protein is weak . The advance of separation techniques as well as the integration and optimization among these techniques has made it possible to separate sexspecific membrane proteins in mammalian spermatozoa.
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Received: 25 January 2006
Published: 25 January 2006
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