Gentic Manipulation on Biosynthesis of Terpenoids

China Biotechnology

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Gentic Manipulation on Biosynthesis of Terpenoids

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Abstract Terpenoids constitute a chemically diverse family of naturally occuring compounds with pharmaceutical significance, such as artemisinin and taxin. They are synthesized in many kinds of microorganisms and plants with very low yield. Metabolic engineering, modifying metabolic pathways of terpenoidssynthesized cells by recombinant DNA techniques, has been developed and applied to improve the production of terpenoids, as well as create a novel biosynthesis pathway of terpenoids in terpenoidfree organisms. The biosynthetic pathway of terpenoids was sumed up, and recent progress of metabolic engineering aiming at raising content of terpenoids in microorganisms and plants was described.

Key words： Metabolic Engineering Terpenoids Gene Tranfer

Received: 20 October 2005 Published: 25 January 2006

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. Gentic Manipulation on Biosynthesis of Terpenoids. China Biotechnology, 2006, 26(01): 60-64.

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https://manu60.magtech.com.cn/biotech/ OR https://manu60.magtech.com.cn/biotech/Y2006/V26/I01/60

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