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Application of Laponite in Tissue Regeneration |
XU Xiong-cheng,LUO Kai() |
Fujian Key Laboratory of Oral Diseases, Stomatological Key Laboratory of Fujian College and University, Institute of Stomatology & Laboratory of Oral Tissue Engineering, School and Hospital of Stomatology, Fujian Medical University, Fuzhou 350002, China |
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Abstract Tissue defects caused by trauma, tumors and congenital developmental abnormalities seriously affect the physiological function and mental health of patients. Processes of tissue regeneration and repair are complex. The body’s ability to regenerate and repair tissue defects gradually weakens, which is mainly based on scar repair with fibrous capsule. Laponite (LAP) has been widely used for functionalized modification of tissue regeneration biomaterials due to its unique nano-layered structure and surface electrochemical characteristics, which can interact with a variety of biomolecules and drugs and exhibit better cytocompatibility and bioactivity. The properties and characteristics of LAP and its application in the field of tissue regeneration and repair are reviewed in order to promote better clinical translation of LAP research outcomes.
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Received: 04 July 2022
Published: 05 January 2023
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Corresponding Authors:
Kai LUO
E-mail: luokai39@163.com
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