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中国生物工程杂志

China Biotechnology
China Biotechnology
China Biotechnology  2021, Vol. 41 Issue (12): 13-23    DOI: 10.13523/j.cb.2111014
    
Research Progress on Maize Genetic Transformation and Commercial Development of Transgenic Maize
HE Wei1,2,ZHU Lei1,2,LIU Xin-ze1,2,AN Xue-li1,2,3,**(),WAN Xiang-yuan1,2,3,**()
1 Research Center of Biology and Agriculture, Shunde Graduate School, School of Chemistry and Biological Engineering, University of Science and Technology Beijing, Beijing 100083, China
2 Zhongzhi International Institute of Agricultural Biosciences, Beijing 100192, China
3 Beijing Engineering Laboratory of Main Crop Bio-Tech Breeding, Beijing International Science and Technology Cooperation Base of Bio-Tech Breeding, Beijing Solidwill Sci-Tech Co., Ltd., Beijing 100192, China
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Abstract  

Maize is the largest cultivated grain crop in the world. To increase maize yield and meet human’s needs, genetic modification has become an effective breeding tool for maize improvement. Since commercial GM (genetically modified) maize was planted in the United States in 1996, genetic transformation has achieved a great success in developing commercialized GM maize. This article reviews the important steps during maize genetic transformation, summarizes the commercial development of transgenic maize varieties, and suggests the optimization of maize genetic transformation system, the safety of transgenic maize, and the commercial development of more GM maize varieties.

Key words： Maize      Genetic transformation      Transgenic maize      Commercial development     
Received: 04 November 2021      Published: 13 January 2022
ZTFLH:  Q819  
Corresponding Authors: Xue-li AN,Xiang-yuan WAN     E-mail: xulian@ustb.edu.cn;wanxiangyuan@ustb.edu.cn
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Wei HE
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Xin-ze LIU
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Cite this article:

HE Wei,ZHU Lei,LIU Xin-ze,AN Xue-li,WAN Xiang-yuan. Research Progress on Maize Genetic Transformation and Commercial Development of Transgenic Maize. China Biotechnology, 2021, 41(12): 13-23.

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https://manu60.magtech.com.cn/biotech/10.13523/j.cb.2111014     OR     https://manu60.magtech.com.cn/biotech/Y2021/V41/I12/13

Fig.1 Schematic illustration of genetic transformation in maize
Fig.2 The mechanism of Cre/LoxP site-specific recombination system LB: T - DNA left border; RB: T-DNA right border; SMG: Selected marker gene; GOI: Gene of interest; Pro: Promoter; Cre: Cyclization recombination enzyme;LoxP: Locus of X(cross)-overinP1 site
Fig.3 The plant areas of global transgenic crop and corn from 1996 to 2019
Table 1 Transgenic maize events with commercial trademarks
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