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| Research Progress of Three-dimensional Genomics in Animal Genetics and Breeding |
CHEN Yi-he1,LI Xin-miao1,PENG Wei2,LEI Chu-zhao1,ZHAO Huang-qing1,ZHANG Zi-jing3,LIU Xian4,HUANG Yong-zhen1,**( ) |
1 College of Animal Science and Technology, Northwest Agriculture and Forestry University, Yangling 712100, China
2 Qinghai Academy of Animal Science and Veterinary Medicine, Qinghai University, Xining 810016, China
3 Institute of Animal Husbandry and Veterinary Science, Henan Academy of Agricultural Sciences, Zhengzhou 450002, China
4 Henan Provincial Animal Husbandry General Station, Zhengzhou 450008, China |
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Abstract Three-dimensional genomics is a newly developed subject that studies the three-dimensional space and structure of genome. Based on considering genome sequence, gene structure and its regulatory elements, it studies the functions of gene replication, transcription, repair and regulation in biological processes and the three-dimensional structure of genome sequence in the nucleus. With the emergence and improvement of high-throughput sequencing technology, the research of three-dimensional genomics has developed rapidly. This paper focuses on the development process, research technology and structural level of three-dimensional genomics, and summarizes the application of three-dimensional genomics in animal genetics and breeding in recent years.
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Received: 27 October 2021
Published: 05 May 2022
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Corresponding Authors:
Yong-zhen HUANG
E-mail: hyzsci@nwafu.edu.cn
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