Please wait a minute...

中国生物工程杂志

China Biotechnology
China Biotechnology  2021, Vol. 41 Issue (10): 116-126    DOI: 10.13523/j.cb.2107015
    
Analysis of Global Bioeconomy Status, Trends and Financing Prospects
WU Xiao-yan,CHEN Fang(),DING Chen-jun,SUN Yu-tong
Chengdu Library and Information Center, Chinese Academy of Sciences,Chengdu 610041, China
Download: HTML   PDF(1238KB) HTML
Export: BibTeX | EndNote (RIS)      

Abstract  

Bioeconomy is the sum of all economic activities that use renewable natural resources to produce food, energy, biotechnology products and services in a sustainable way. Bioeconomy is the fourth wave of human economic and social development after agricultural economy, industrial economy and information economy. This paper outlines the current situation of global bioeconomy development, sorts out the bioeconomic strategic layout of the world’s major economies, and sums up the four main directions for future development of the bioeconomy. Through analysis of the investment data of three key areas of bio-industry, it predicts the future investment prospects of the bio-industry, and puts forward some suggestions on investment of bio-industry in China. The purpose of this paper is to provide reference information for the development and value investment of the bio-industry for the participants and related parties, in order to promote the transfer and transformation of scientific and technological achievements, technology capital docking and development of the bio-industry, and make contributions to the sustainable development of China’s economy and society.



Key wordsBio-economy      Bio-industry      Bio-manufacturing      Industrial financing     
Received: 05 July 2021      Published: 08 November 2021
ZTFLH:  Q-1  
Corresponding Authors: Fang CHEN     E-mail: chenf@clas.ac.cn
Cite this article:

WU Xiao-yan,CHEN Fang,DING Chen-jun,SUN Yu-tong. Analysis of Global Bioeconomy Status, Trends and Financing Prospects. China Biotechnology, 2021, 41(10): 116-126.

URL:

https://manu60.magtech.com.cn/biotech/10.13523/j.cb.2107015     OR     https://manu60.magtech.com.cn/biotech/Y2021/V41/I10/116

Fig.1 Annual distribution of financing in the biopharmaceutical field
Fig.2 Country distribution of financing in biopharmaceutical filed
Fig.3 Distribution of financing stages in the biopharmaceutical field
主营业务 国别 企业名称 上市日期 融资金额/百万美元
生物药产业对接 美国 Royalty Pharma 2020-06-16 2 176
肿瘤药 中国 德琪医药 2020-11-20 1 183.12
疫苗 中国 康希诺 2020-08-13 804.59
抗体药 中国 君实生物 2020-07-15 755.383 2
工程细胞药物 美国 Sana Biotechnology 2021-02-04 588
抗体药物 中国 荣昌生物 2020-11-09 512.856 8
抗体药物 丹麦 Genmab 2019-07-18 505.9
抗体药物 加拿大 Abcellera Biologics 2020-12-10 482
机器学习药物研发 美国 Recursion Pharmaceuticals 2021-04-16 455
生物制药 中国 复宏汉霖 2019-06-25 441.2
CAR-T疗法 中国 传奇生物 2020-06-05 424
蛋白药物 美国 Relay Therapeutics 2020-07-15 400
Table 1 Financing situation of representative newly listed companies in the biopharmaceutical field
主营业务 国别 企业名称 融资日期 融资阶段 融资金额/百万美元
生物制药服务 美国 National Resilience 2020-11-23 B 750
工程细胞药物 美国 Sana Biotechnology 2020-06-29 A 700
基因疗法 瑞士 Fergene 2019-11-27 战略融资 570
细胞疗法 美国 Elevatebio 2021-03-15 C 525
疫苗生产 中国 科兴中维 2020-12-06 战略融资 515
癌症药物的研发 美国 EQRx 2021-01-12 B 500
T细胞疗法 美国 Lyell Immunopharma 2010-03-12 C 493
生物靶向药 德国 BioNtech 2019-07-09 B 325
生物疫苗 德国 CureVac 2020-06-16 战略融资 356.22
新冠疫苗抗体药物 美国 Adagio Therapeutics 2021-04-20 C 336
免疫治疗 美国 Vir Biotechnology 2019-01-01 B 327.6
难治性疾病药物 中国 LianBio 2020-10-01 A 310
抗体药物 中国 云顶新耀 2020-06-05 C 310
抗体药物 中国 迈威生物 2020-04-28 A 308.108
抗体药物 瑞士 ADC Therapeutics 2019-06-14 E 303
Table 2 Financing situation of representative new enterprises in the biopharmaceutical field
Fig.4 Annual distribution of financing in biomaterials/biochemicals field
Fig.5 Country distribution of financing in biomaterials/biochemicals field
Fig.6 Distribution of financing stages in biomaterials/biochemicals field
主营业务 国别 企业名称 融资日期 融资阶段 金额 /百万美元
生物塑料 中国 凯赛生物 2020-08-12 IPO 784.7
生物化学品 美国 Amyris Biotechnologies 2020-06-07 IPO后股权融资 200
2021-04-09 IPO后股权融资 300
生物聚合物 美国 Danimer Scientific 2020-12-29 IPO后融资 210
生物燃料 美国 Benson Hill Biosystems 2020-10-29 D 150
生物塑料 新加坡 RWDC Industries 2020-05-05 B 133
生物化学品 美国 Greenlight Biosciences 2020-05-12 风险投资 17
2020-06-16 D 102
乳酸 中国 金丹科技 2020-04-22 IPO 98.76
丙氨酸 中国 华恒生物 2021-04-22 IPO 96.75
生物化学品 美国 Codexis 2020-12-02 IPO后股权融资 75
生物化学品 美国 Manus Bio 2020-11-17 B 75
生物材料 美国 Ecovative Design 2021-03-30 D 60
生物能源 美国 Renmatix 2020-03-24 风险投资 48.6
生物材料 美国 Checkerspot 2020-05-04 B 36
生物材料 德国 AMSilk 2021-05-11 C 35.28
微生物 中国 蓝晶微生物 2020-05-01 A+ 1.49
2021-02-26 B 30.98
Table 3 Financing situation of representative biomaterial/biochemical enterprises
Fig.7 Annual distribution of financing in bioagriculture/future food field
Fig.8 Countries distribution of financing in bioagriculture/future food field
Fig.9 Distribution of financing stages in bioagriculture/future food field
主营业务 国别 企业名称 融资时间 融资阶段 融资额/百万美元
植物蛋白肉 美国 Impossible Foods 2020-03-16 F 500
2020-08-13 G轮 200
微生物种子保护剂 美国 Indigo 2020-08-03 F 360
2020-01-06 F 175
2020-01-06 债务融资 25
农业保鲜 美国 Apeel Sciences 2020-05-26 D 250
2020-10-27 风险投资 30
农业育种 美国 InariAgriculture 2020-04-22 债务融资 45
2021-05-12 D 208
动物细胞培养肉 美国 Memphis Meats 2020-01-22 B 161
人造蛋白 美国 Perfect Day Foods 2020-07-08 C 160
人造肉 美国 Modern Meadow 2021-04-29 C 130
高效生物肥料 美国 Anuvia Plant Nutrients 2020-09-30 C 60.2
2021-02-23 C 103
可持续作物解决方案 美国 Green Light Biosciences 2020-05-12 风险投资 17
2020-06-16 D 102
作物保护 美国 Pivot Bio 2020-04-30 C 100
人造蛋白 美国 Geltor 2020-07-27 B 91.3
农业基因编辑 美国 PairwisePlants 2021-02-03 B 90
人造蛋白 美国 Nature’s Fynd 2020-03-24 B 80
2020-12-08 债务融资 45
微生物肥料 美国 Ginkgo Bioworks 2020-05-28 F 70
植物基人造肉 中国 Green Monday 2020-09-22 A 70
Table 4 Financing situation of representative bioagriculture/future food enterprises
[1]   Bioeconomy BW. What is a bioeconomy. [2021-06-15]. https://www.biooekonomie-bw.de/en/bw/definition.
[2]   McKinsey Global Institute. The bio revolution: innovations transforming economies, societies, and our lives.[2020-05-13]. https://www.mckinsey.com/industries/pharmaceuticals-and-medical-products/our-insights/the-bio-revolution-innovations-transforming-economies-societies-and-our-lives#.
[3]   OECD. The bioeconomy to 2030: designing a policy agenda.[2009-04-15]. https://www.oecd.org/futures/long-termtechnologicalsocietalchallenges/thebioeconomyto2030designingapolicyagenda.htm.
[4]   OECD. Meeting policy challenges for a sustainable bioeconomy.[2018-04-19]. https://www.oecd.org/sti/policy-challenges-facing-a-sustainable-bioeconomy-9789264292345-en.htm.
[5]   USDA. Strong bioproducts sector growth nationwide leads to equally strong job gains.[2018-06-15]. https://biopreferred.gov/BioPreferred/faces/pages/articles/EconAnalysis2018.xhtml.
[6]   The Biomass Research and Development Board. Bioeconomy initiative implementation framework.[2019-03-05]. https://biomassboard.gov/../pdfs/Bioeconomy_Initiative_Implementation_Framework_FINAL.pdf.
[7]   The National Academies of Sciences Engineering Medicine. Safeguarding the bioeconomy.[2020-06-15]. https://www.nap.edu/catalog/25525/safeguarding-the-bioeconomy.
[8]   116th Congress. Bioeconomy research and development act of 2020.[2020-05-14]. https://www.congress.gov/bill/116th-congress/senate-bill/3734/text.
[9]   Nova Institution. Bioeconomy worth 2.4 trillion EUR to the European economy as bio-based industries mark sizeable jump in turnover and bio-based share of chemicals reaches record high of 15%.[2020-09-07]. https://biconsortium.eu/sites/biconsortium.eu/files/downloads/PR%20-%20Bioeconomy%20worth%202.4%20trillion%20EUR%20to%20the%20European%20economy%20as%20bio-based%20industries%20mark%20sizeable%20jump%20in%20turnover.pdf.
[10]   European Commission. A sustainable bioeconomy for Europe: strengthening the connection between economy, society and the environment: updated bioeconomy strategy. [2018-10-11]. https://knowledge4policy.ec.europa.eu/publication/sustainable-bioeconomy-europe-strengthening-connection-between-economy-society_en#:~:text=A%20sustainable%20bioeconomy%20for%20Europe%20-%20strengthening%20the,Goals%20%28SDGs%29%2C%20as%20well%20as%20the%20Paris%20Agreement.
[11]   BIC. The strategic innovation and research agenda (SIRA 2030) for a circular bio-based Europe.[2020-03-20]. https://biconsortium.eu/sites/biconsortium.eu/files/documents/Draft%20SIRA%202030%20-%20March%202020.pdf.
[12]   European Commission. Foresight scenarios for the EU bioeconomy in 2050. [2021-06-15]. https://ec.europa.eu/jrc/en/news/european-bioeconomy-2050-four-foresight-scenarios.
[13]   UK Research and Innovation. Forward look for UK bioscience.[2018-09-27]. https://bbsrc.ukri.org/documents/forward-look-for-uk-bioscience-pdf/.
[14]   Department for Business, Energy & Industrial. Strategy growing the bioeconomy: improving lives and strengthening our economy: a national bioeconomy strategy to 2030. [2018-09-27]. https://www.gov.uk/government/publications/bioeconomy-strategy-2018-to-2030/growing-the-bioeconomy-a-national-bioeconomy-strategy-to-2030.
[15]   EFI. Investing in nature to transform the post COVID-19 economy.[2020-10-06]. https://www.efi.int/news/investing-nature-transform-post-covid-19-economy-2020-06-10.
[16]   HM Government. UK research and development roadmap. [2020-07-01]. https://www.gov.uk/government/publications/uk-research-and-development-roadmap.
[17]   統合イノベーション戦略推進会議. バイオ戦略2020.[2021-06-15]. https://www8.cao.go.jp/cstp/bio/bio2020_honbun.pdf.
[17]   Conference on Promoting Comprehensive Innovation Strategy. 2020 Biostrategy. [2021-06-15]. https://www8.cao.go.jp/cstp/bio/bio2020_honbun.pdf
[18]   国家发展改革委. “十三五”生物产业发展规划.[2017-01-12]. http://www.gov.cn/xinwen/2017-01/12/5159179/files/516df96cc5254eb4976d14708e14056f.pdf.
[18]   National Development and Reform Commission. 13th Five-year plan for the development of biological industry.[2017-01-12]. http://www.gov.cn/xinwen/2017-01/12/5159179/files/516df96cc5254eb4976d14708e14056f.pdf.
[19]   科技部. “十三五”生物技术创新专项规划. [2017-04-24]. https://yiliao.usst.edu.cn/_upload/article/files/9d/21/2aa8097d402e88a41bc5499cf173/5e765362-0bb2-441f-b669-a2a3ec326c97.pdf.
[19]   Ministry of Science and Technology. 13th Five-year plan for biotechnology innovation.[2017-04-24]. https://yiliao.usst.edu.cn/_upload/article/files/9d/21/2aa8097d402e88a41bc5499cf173/5e765362-0bb2-441f-b669-a2a3ec326c97.pdf.
[20]   前瞻经济学人. 2021年全球及中国生物药市场规模与发展前景分析市场规模快速增长. [2021-05-31]. https://baijiahao.baidu.com/s?id=1701265092137296111&wfr=spider&for=pc.
[20]   Forward-looking Economist. Market size and development prospect analysis of global and Chinese biopharmaceutical market in 2021. [2021-05-31]. https://baijiahao.baidu.com/s?id=1701265092137296111&wfr=spider&for=pc.
[1] WU Xiao-yan,CHEN Fang,DING Chen-jun,ZHENG Ying,SONG Qi. Analysis of the Global Biomanufacturing Industry Market and Financing Status[J]. China Biotechnology, 2020, 40(5): 117-124.
[2] Fang CHEN,Yun-wei CHEN,Chen-jun DING,Ying ZHENG,Xiao-yan WU,Dan-dan LUO,Qiu-wei ZHAO,Bo YU. A Study on the Trends of Biotechnology Development in Countries along the Belt and Road[J]. China Biotechnology, 2018, 38(1): 1-14.
[3] CHEN Fang, DING Chen-jun, CHEN Yun-wei, ZHENG Ying, DENG Yong, XU Ping, YU Jian-rong, WU Lin-huan, MA Jun-cai, ZENG Yan, LIU Bin. A Study on the Trend and Prospective of Industrial Biotechnology in China[J]. China Biotechnology, 2016, 36(5): 1-11.