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Research Progress on miR-146a Involved in Different Diseases |
ZHU Jia-hao,CHEN Ting,XI Qian-yun() |
National Engineering Research Center for Breeding Swine Industry /Key Laboratory of Animal Nutrition Control in Guangdong, College of Animal Science, South China Agricultural University, Guangzhou 510642, China |
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Abstract miR-146a is a hot topic in recent miRNA study and keeps highly conserved in different species. It is involved in the occurrence and development of various types of diseases, such as inflammation, autoimmune diseases, cancer and obesity, and its mechanism mainly plays a role through TLR4, MyD88, NF-κB and Akt signaling pathways. In this paper, the roles and mechanisms of miR-146a in different disease processes are reviewed to provide information for further research on the regulatory role of miR-146a in various diseases.
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Received: 08 June 2021
Published: 30 September 2021
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Corresponding Authors:
Qian-yun XI
E-mail: xqy0228@163.com
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