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| Research Progress of Relationship between Exosomes and Autophagosomes |
Yan LIU1,2,Peng DAI2,Yun-feng ZHU1,3,**( ) |
1 College of Life Sciences and Bioengineering,Beijing Jiaotong University,Beijing 100044,China
2 Henan Province OriginBio Biotechnology Co. Ltd., Zhengzhou 450000, China
3 The Key Laboratory of Tumor Center in PLA General Hospital, Beijing 100853, China |
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Abstract The eukaryotic intima system consists of intercellular membranous organelles, including the formation of exosomes and autophagy, which play an important role in stress response and maintenance of cell homeostasis. Exosomes are extracellular vesicles secreted into the body by multivesicular bodies containing contents of proteins and nuclear acids, while autophagy is a process of lysosomal-dependent degradation and recycling. There is a common molecular mechanism between the formation of exosomes and autophagy, and substantial interaction between them were founded.The formation of exosomes and the process of autophagy was reviewed, including the relationship between the two and lysosomes.
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Received: 13 November 2018
Published: 12 July 2019
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Corresponding Authors:
Yun-feng ZHU
E-mail: zhuyf2004@163.com
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