| Orginal Article |
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| Application of Second Generation Gene Sequencing Data Management and Big Data Platform in Precision Medicine |
Ao-shen WU,Xiao-na LIU,Yun-he LIU,Gang LIU,Lei LIU( ) |
| Institute of Biological Sciences, Fudan University, Beijing 200032,China |
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Abstract Precision medicine integrates multiple types of data, including -omics, clinical, environmental and behavioral data to facilitate the personalized therapy, prevention and management. The cost reduction of gene/genome sequencing, the understanding of cancers from pathology to molecular level, and improvement of some subjects and technologies promoted the formation and development of precision medicine. The precision medicine will have a huge impact on human health. In this article, concept, purpose and application of precision was introduced, and application of next-generation DNA sequencing in precision medicine was also presented. The foundation of the precision medicine is genomic data, sample management of samples, and data quality control. Artificial intelligence is the future of precision medicine. Meanwhile, the characteristics of genomic data and the management of various health-related data are also a huge challenge for precision medicine.
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Received: 10 January 2019
Published: 26 March 2019
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