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| Research Progress of Lipoprotein in Gram-positive Bacteria |
Xiao-fang WU,Jia-heng LIU,Hui XIONG,Jian-jun QIAO,Hong-ji ZHU( ) |
| School of Chemical Engineering and Technology, Key Laboratory of Systems Bioengineering of Ministry of Education, SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering, Tianjin University, Tianjin 300072, China |
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Abstract As important components of cell membrane,bacterial lipoproteins play critical roles in many physiological process of bacteria, such as nutrient acquisition, environmental sensing, maintaining cell envelope and cell wall stability and electron transfer. With the continuous development and improvement of biotechnology, more and more lipoprotein as well as their functions have been discovered. This paper reviews the research progress of lipoprotein functions, biosynthesis and applications in Gram-positive bacteria. The influence of Lgt and LspA, key enzymes in lipoprotein biosynthesis, on physiological activity of Gram-positive bacteria is also addressed. Finally, the prospect and suggestion are provided for the future research on Gram-positive bacteria lipoproteins.
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Received: 09 March 2018
Published: 06 July 2018
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Corresponding Authors:
Hong-ji ZHU
E-mail: zhj@tju.edu.cn
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