New Progress in the Study of <i>Streptococcus suis</i> Type 2 Virulence Factors

doi:10.13523/j.cb.20180313

China Biotechnology

2018, Vol. 38

Issue (3): 97-104 DOI: 10.13523/j.cb.20180313

Orginal Article

New Progress in the Study of Streptococcus suis Type 2 Virulence Factors

Jing-xian LIU¹,Xin HE^1*(

),Hui-ming HAN^1,^2*(

)

1 Basic Medical College, Beihua University, Jilin 132013, China
2 The Clinical Immunology Research Center, Beihua University, Jilin　132013, China

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Abstract

Streptococcus suis is an infectious Gram-positive bacterium. Streptococcus suis serotype 2 (S. suis 2, SS2) is an important zoonotic pathogen that severely affects the swine breeding industry and causes human mortality rates of between 5% and 20%. Its virulence factors play an important role in the pathogenesis. In recent years, there were many new advances in the virulence factors of SS2. in the pathogenic mechanism, and there were either new knowledge for effective prevention and control of the disease. The recent progress in the virulence-related factors of SS2, e.g. proteins, enzymes, the virulence factor gene expression two-component system and type IV secretion system which interaction to host immune system were summarized. There were valuable references for the treatment of SS2 and vaccine development.

Key words： Streptococcus suis serotype 2 Virulence factor Pathogenesis

Received: 20 December 2017 Published: 04 April 2018

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Cite this article:

Jing-xian LIU,Xin HE,Hui-ming HAN. New Progress in the Study of Streptococcus suis Type 2 Virulence Factors. China Biotechnology, 2018, 38(3): 97-104.

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https://manu60.magtech.com.cn/biotech/10.13523/j.cb.20180313 OR https://manu60.magtech.com.cn/biotech/Y2018/V38/I3/97


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