| Orginal Article |
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| Advances in the Research of Genetically Engineering Vaccine of Mycoplasmal pneumoniae |
Yu TAO1,Gao-jian LI1,Jian-hong SHU1,Yue-hong WU1,Fang YANG2,Yu-long HE1*( ) |
1 College of Life Sciences, Zhejiang Sci-Tech University, Hangzhou 310018, China
2 Hangzhou Hong Sheng Biotechnology Limited by Share Ltd, Hangzhou 310018, China |
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Abstract Mycoplasmal pneumoniae of swine (MPS) is a chronic respiratory infectious disease caused by Mycoplasma hyopneumonia (Mhp), thus causes huge losses to the pig industry. At present, vaccination is the main means to reduce or prevent the economic losses caused by Mycoplasma pneumoniae. The research progress of gene engineering vaccine of Mycoplasmal pneumoniae of swine in recent years is discussed, mainly includes adhesion factors related vaccines, ribonucleotide reductase related vaccines, DNA vaccines, expression library vaccines and peptide vaccines, etc. Finally, suggestions for the development of genetic engineering vaccines are proposed.
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Received: 28 July 2017
Published: 21 March 2018
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