[1] Go A S, Mozaffarian D, Roger V L,et al.Heart disease and stroke statistics-2014 update:a report from the American Heart Association.Circulation, 2014, 129(3):e28-e292.
[2] Dilley R J, Morrison W A.Vascularisation to improve translational potential of tissue engineering systems for cardiac repair.Int J Biochem Cell Biol, 2014, 56:38-46.
[3] Jaenisch R, Young R.Stem cells,the molecular circuitry of pluripotency and nuclear reprogramming.Cell, 2008, 132(4):567-582.
[4] Polo J M, Liu S, Figueroa M E, et al.Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells.Nat Biotechnol, 2010, 28(8):848-855.
[5] Muraoka N, Yamakawa H, Miyamoto K, et al.MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures.EMBO J, 2014, 33(14):1565-1581.
[6] Pfisterer U, Kirkeby A, Torper O, et al.Direct conversion of human fibroblasts to dopaminergic neurons.Proc Natl Acad Sci U S A, 2011, 108(25):10343-10348.
[7] Davis R L, Weintraub H, Lassar A B.Expression of a single transfected cDNA converts fibroblasts to myoblasts.Cell, 1987, 51(6):987-1000.
[8] Blau H M, Pavlath G K, Hardeman E C, et al.Plasticity of the differentiated state.Science, 1985, 230(4727):758-766.
[9] Vierbuchen T, Ostermeier A, Pang Z P, et al.Direct conversion of fibroblasts to functional neurons by defined factors.Nature, 2010, 463(7284):1035-1041.
[10] Kelly M C, Chang Q, Pan A, et al.Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo.J Neurosci, 2012, 32(19):6699-6710.
[11] Liu Z, Dearman J A, Cox B C, et al.Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression.J Neurosci, 2012, 32(19):6600-6610.
[12] Buganim Y, Itskovich E, Hu Y C, et al.Direct reprogramming of fibroblasts into embryonic sertoli-like cells by defined factors.Cell Stem Cell, 2012, 11(3):373-386.
[13] Takahashi K, Yamanaka S.Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.Cell, 2006, 126(4):663-676.
[14] Ieda M, Fu J D, Delgado-Olguin P, et al.Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors.Cell, 2010, 142(3):375-386.
[15] Song K, Nam Y J, Luo X, et al.Heart repair by reprogramming non-myocytes with cardiac transcription factors.Nature, 2012, 485(7400):599-604.
[16] Protze S, Khattak S, Poulet C, et al.A new approach to transcription factor screening for reprogramming of fibroblasts to cardiomyocyte-like cells.J Mol Cell Cardiol, 2012, 53(3):323-332.
[17] Chen J X, Krane M, Deutsh M A, et al.Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4,Mef2c,and Tbx.Circ Res, 2012, 111(1):50-55.
[18] Inagawa K, Ieda M.Direct reprogramming of mouse fibroblasts into cardiac myocytes.J Cardiovasc Transl Res, 2013, 6(1):37-45.
[19] Jayawardena T M, Egemnazarov B, Finch E A, et al.MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes.Circ Res, 2012, 110(11):1465-1473.
[20] Muraoka N, Yamakawa H, Miyamoto K, et al.MiR-133 promotes cardiac reprogramming by directly repressing Snai1 and silencing fibroblast signatures.EMBO J, 2014, 33(14):1565-1581.
[21] Wang H, Cao N, Spencer C I, et al.Small molecules enable cardiac eprogramming of mouse fibroblasts with a single factor,Oct4.Cell Rep, 2014, 6(5):951-960.
[22] Ifkovits J L, Addis R C, Epstein J A, et al.Inhibition of TGFβ signaling increases direct conversion of fibroblasts to induced cardiomyocytes.PloS One, 2014, 9(2):e89678.
[23] Russell C Addis, Jonathan A Epstein.Induced regeneration-the progress and promise of direct reprogramming for heart repair.Nat Med, 2013, 19(7):829-836.
[24] Qian L, Huang Y, Spencer C I, et al.In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes.Nature, 2012, 485(7400):593-598.
[25] Fu J D, Stone N R, Liu L, et al.Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state.Stem Cell Reports, 2013, 1(3):235-247.
[26] Islas J F, Liu Y, Weng K C, et al.Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors.Proc Natl Acad Sci USA, 2012, 109(32):13016-13021.
[27] Nam Y J, Song K, Luo X, et al.Reprogramming of human fibroblasts toward a cardiac fate.Proc Natl Acad Sci U S A, 2013, 110(14):5588-5593.
[28] Wada R, Muraoka N, Inagawa K, et al.Induction of human cardiomyocyte-like cells from fibroblasts by defined factors.Proc Natl Acad Sci U S A, 2013, 110(31):12667-12672.
[29] Yamakawa H, Ieda M.Strategies for heart regeneration approaches ranging from induced pluripotent stem cells to direct cardiac reprogramming.Int Heart J, 2015, 56(1):1-5.
[30] Kattman S J, Koonce C H, Walison B J, et al.Stem cells and their derivatives:A renaisance in cardiovaseular translational research.J Cardiovase Tranal Res, 2011, 4(1):66-72.
[31] Xie M, Cao N, Ding S.Small molecules for cell reprogramming and heart repair:Progress and perspective.ACS Chem Biol, 2014, 9(1):34-44.
[32] Nam Y J, Lubczyk C, Bhakta M, et al.Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors.Development, 2014, 141(22):4267-4278. |