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中国生物工程杂志

China Biotechnology
China Biotechnology  2014, Vol. 34 Issue (8): 112-116    DOI: 10.13523/j.cb.20140817
    
Three-dimensional Construction of Tissue Organ and Concept of in situ Tissue Engineering
WANG Dian-liang
Tissue Engineering and Regenerative Medicine Laboratory, The Second Artillery General Hospital, Beijing 100088, China
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Abstract  

Tissue organ three-dimensional construction is that seed cells are combined with scaffold material to obtain the designed tissue or organ, which is a main content of tissue engineering and can represent technological merits of tissue engineering, such as the construction of blood vessel and trachea. For the flaws of traditional tissue engineering, Shimizu firstly put forward the concept of in situ tissue engineering, which applies the basic principle of tissue engineering to develop new tissue to repair defects by means of the transplanted seed cells induced by every method or the migration, proliferation and differentiation of the local cells of endogenic defect tissues. The distinctive characteristic of in situ tissue engineering is that bioreactor, an in vitro cell culture apparatus, is independent. In situ tissue engineering is a beneficial supplement of traditional ex vivo tissue engineering, which still has vast potentials for future development.



Key wordsTissue organ      Tissue engineering      Three-dimensional construction      In situ tissue engineering      Ex vivo tissue engineering     
Received: 15 July 2014      Published: 25 August 2014
ZTFLH:  Q819  
Cite this article:

WANG Dian-liang. Three-dimensional Construction of Tissue Organ and Concept of in situ Tissue Engineering. China Biotechnology, 2014, 34(8): 112-116.

URL:

https://manu60.magtech.com.cn/biotech/10.13523/j.cb.20140817     OR     https://manu60.magtech.com.cn/biotech/Y2014/V34/I8/112


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