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Research Progress on Separation and Purification of Mannan Oligosaccharide |
PAN Bing-jv,ZHANG Wan-yi,SHEN Hui-tao,LIU Ting-ting,LI Zhong-yuan,LUO Xue-gang,SONG Ya-jian() |
College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China |
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Abstract Mannan oligosaccharides have a series of physiological functions such as, lower blood fat, resist colon inflammation, enhance immunity and regulate intestinal flora and have broad application prospects in the fields of food and medicine. The mannan-oligosaccharide products prepared by the hydrolysis method usually contain monosaccharides, unhydrolyzed polysaccharides, oligosaccharides with different polymerization degree, salt ions and other impurities, which need further separation and purification. The main purification methods of mannose oligosaccharides in recent years are reviewed, including column chromatography, membrane separation, ethanol precipitation and microbial fermentation. The principle, application scope and application examples of various methods are summarized, and the advantages and disadvantages of different methods are analyzed.
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Received: 21 July 2020
Published: 11 December 2020
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Corresponding Authors:
Ya-jian SONG
E-mail: songyajian@tust.edu.cn
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