Research Progress of Polydopamine Modified Polymers in Nerve Repair

doi:10.13523/j.cb.2006033

China Biotechnology

2020, Vol. 40

Issue (10): 57-64 DOI: 10.13523/j.cb.2006033

Research Progress of Polydopamine Modified Polymers in Nerve Repair

LIU Zi-ru,ZHANG Tian(

)

School of Chemistry,Chemical Engineering and Life Sciences, Wuhan University of Technology, Wuhan 430070,China

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Abstract

Inspired by the adhesion of mussels, the researchers found that dopamine self-polymerizes to form polydopamine under alkaline conditions. Due to its strong adhesion properties, polydopamine has been widely used to modify various biological materials in the past few years. Most of the materials used in nerve repair are polymers, but the effect of using polymers alone to repair nerves is not good. Polydopamine modified polymers have better hydrophilicity and biocompatibility than single polymers. In addition, the polydopamine coating on the polymer can be used to further modify the molecules that promote nerve repair. This article reviews the synthesis mechanism and performance of polydopamine and the research progress of polydopamine-modified polymers in nerve repair, and at the end of the article, the development prospects of such materials are prospected.

Key words： Polydopamine Polymer Nerve repair

Received: 22 June 2020 Published: 10 November 2020

ZTFLH:

R318.08

Corresponding Authors: Tian ZHANG E-mail: tzhang@whut.edu.cn

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Cite this article:

LIU Zi-ru,ZHANG Tian. Research Progress of Polydopamine Modified Polymers in Nerve Repair. China Biotechnology, 2020, 40(10): 57-64.

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https://manu60.magtech.com.cn/biotech/10.13523/j.cb.2006033 OR https://manu60.magtech.com.cn/biotech/Y2020/V40/I10/57

Fig.1 Schematic diagram of polydopamine modified polymer material


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