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| Advances in Rhamnolipid Biosynthesis by Pseudomonas aeruginosa Research |
DUAN Hai-rong1,3,WEI Sai-jin1,3,LI Xun-hang2,3,**( ) |
1 College of Biological Science and Engineering, Jiangxi Agricultural University, Nanchang 330045,China
2 Yuzhang Normal University, Nanchang 330103,China
3 Institute of Applied Microbiology Jiangxi Agricultural University, Nanchang 330045,China |
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Abstract Rhamnolipids have emerged as a very promising alternatives to their chemo-synthetic counterparts, due to their environmental compatibility and the remarkable physicochemical properties. In recent years, rhamnolipids have been intensively studied, aiming to large-scale improve the production of rhamnolipids based on low-cost renewable resources. However, the current findings are insufficient to screen over-producing rhamnolipids strains with competitive commercial values. Therefore, it is imperative to in-depth understand the sophisticated gene regulatory network of rhamnolipids biosynthesis and explore the fermentation technology to lower the costs. The biosynthetic pathways and the main gene regulatory factors by quorum sensing involved in rhamnolipids production within Pseudomonas aeruginosa are presented, followed by the role of in biofilm formation, and the effect of fermentation optimization on rhamnolipids yield. It is helpful to enhance our understanding on rhamnolipids biosynthesis and provide important reference information for improving the yield of rhamnolipids.
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Received: 13 May 2020
Published: 12 October 2020
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Corresponding Authors:
Xun-hang LI
E-mail: li_xunh@126.com
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