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中国生物工程杂志

China Biotechnology
China Biotechnology  2020, Vol. 40 Issue (5): 1-6    DOI: 10.13523/j.cb.2003076
    
Development and Prospect of Antibody Drugs for SARS-CoV-2
WU Rui-jun,LI Zhi-fei,ZHANG Xin,PU Run,AO Yi(),SUN Yan-rong()
China National Center for Biotechnology Development, Beijing 100039,China
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Abstract  

With their unique advantages of high affinity and high specificity, antibody drugs have played an increasingly important role in the diagnosis and treatment of malignant tumors, autoimmune diseases, and infectious diseases, becoming the focus of international innovative drug research. Since the outbreak of COVID-19, many research institutions and enterprises at home and abroad are in accelerated development of antibody drugs. In this situation, a systematic analysis of the status and trends of antibody drugs, the research progress of new antibody drugs for SARS-CoV-2, and the opportunities, challenges and suggestions for current antibody drug innovation in China is of great significance to promote the independent innovation of antibody drugs in China.



Key wordsSARS-CoV-2      Antibody drugs      Drug research      Coronavirus disease 2019(COVID-19)     
Received: 30 March 2020      Published: 02 June 2020
ZTFLH:  Q78  
Corresponding Authors: Yi AO,Yan-rong SUN     E-mail: aoyi@cncbd.org.cn;sunry@cncbd.org.cn
Cite this article:

WU Rui-jun,LI Zhi-fei,ZHANG Xin,PU Run,AO Yi,SUN Yan-rong. Development and Prospect of Antibody Drugs for SARS-CoV-2. China Biotechnology, 2020, 40(5): 1-6.

URL:

https://manu60.magtech.com.cn/biotech/10.13523/j.cb.2003076     OR     https://manu60.magtech.com.cn/biotech/Y2020/V40/I5/1

Fig.1 Schematic diagram of antibody structure(a)and Technology roadmap for monoclonal antibody(b)
Fig.2 Summary of FDA-approved number of new drugs and antibody drugs (2010~2019)[9]
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