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中国生物工程杂志

China Biotechnology
China Biotechnology  2020, Vol. 40 Issue (1-2): 51-56    DOI: 10.13523/j.cb.2002104
Orginal Article     
Patent Situation Analysis of Diagnosis Technology for Coronavirus Infection in Human
ZHAO Ping,YANG Yan-ping()
National Science Library, Chinese Academy of Sciences, Beijing 100190, China
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Abstract  

Since the outbreak of Corona Virus Disease 2019, the speed of diagnosis has been accelerated with the increase of virus detection. This is of great significance for the early treatment and isolation of coronavirus pneumonia patients and the control of the spread of the epidemic. In this paper, based on the patent information for quantitative data analysis, combined with qualitative research, objective display of coronavirus diagnosis technology research and development status. Through the patent application trend, protection market, important patentees, important patents and other dimensions, this paper shows the patent protection profile of coronavirus diagnosis technology, and predicts the future development direction, in order to support the innovation and research of coronavirus diagnosis technology in China.



Key wordsCoronavirus      Diagnosis      Patent     
Received: 11 February 2020      Published: 27 March 2020
ZTFLH:  Q819  
Corresponding Authors: Yan-ping YANG     E-mail: yangyp@mail.las.ac.cn
Cite this article:

ZHAO Ping,YANG Yan-ping. Patent Situation Analysis of Diagnosis Technology for Coronavirus Infection in Human. China Biotechnology, 2020, 40(1-2): 51-56.

URL:

https://manu60.magtech.com.cn/biotech/10.13523/j.cb.2002104     OR     https://manu60.magtech.com.cn/biotech/Y2020/V40/I1-2/51

Fig.1 Domestic and foreign patent application trends
专利受理国 专利件数 技术来源国 专利件数
中国 153 美国 155
美国 91 中国 142
韩国 36 韩国 41
日本 22 荷兰 36
加拿大 20 法国 24
澳大利亚 14 加拿大 19
印度 11 日本 19
新加坡 6 新加坡 19
德国 5 德国 5
俄罗斯 5 西班牙 5
俄罗斯 5
Table 1 Major patent publication countries and origin technology countries(TOP 10)
Fig.2 Main technology distribution of coronavirus diagnostic
Fig.3 Main technology patent application trends of coronavirus diagnostic
Fig. 4 Main application areas
Fig.5 Globally important patent applicants
Fig.6 Important patent applicants in China
公开(公告)号 标题 技术应用 申请日 申请人 在华专利
法律状态
WO2005017133A1 冠状病毒、核酸、蛋白质及用于产生疫苗、药物和诊断剂的方法 HCoV-NL63病毒的核酸诊断和检测 2004/8/18 阿姆斯特丹病毒基因组学研究院股份有限公司 授权有效
EP1470218B1 包含功能性缺失的基因组的冠状病毒样颗粒 免疫检测 2002/5/17 乌得勒支大学; 科学技术基金会 授权有效
CN1483737A 非典型性肺炎病毒特异蛋白质和临床检测的方法及试剂盒 SARS病毒免疫检测 2003/4/26 杭州华大基因研发中心 授权有效
CN1469126A 检测SARS冠状病毒抗体的方法及其试剂盒 SARS病毒核酸检测 2003/4/26 杭州华大基因研发中心; 中国人民解放军军事医学科学院微生物流行病研究所 授权有效
Table 2 Important Patents
[1]   钱炳旭 . 猪德尔塔冠状病毒抗原及抗体检测方法的建立. 扬州: 扬州大学, 2019.
[1]   Qian B X . Establishment of detection method for antigen and antibody of Porcine Deltacoronavirus. Yangzhou:Yangzhou University, 2019.
[2]   台湾马偕纪念医院. 专利名:一种用以检测严重急性呼吸道症候群冠狀病毒之特异性胜抗原及其方法. 中国台湾, TW092132064.20050516[2020028]. Incopat数据库.
[3]   修乐山 . 基于多重PCR-质谱的冠状病毒高通量检测方法的建立与应用. 北京: 北京协和医学院, 2018.
[3]   Xiu L S . Establishment and Application of High-throughput Detection of Coronavirus Based on Multiplex PCR-Mass Spectrometry. Beijing:Peking Union Medical College, 2018.
[4]   Doan T, Pinsky BA . Current and future molecular diagnostics for ocular infectious diseases. Curr Opin Ophthalmol. 2016,27(6):561-567.
[5]   国家卫生健康委办公厅. 《新型冠状病毒肺炎实验室检测技术指南(第二版)》. [2020028]. http://med.china.com.cn/content/pid/158678/tid/1026.
[6]   庄向婷, 白军, 张振仓 . 新型分子诊断技术在动物疫病检测中的应用与发展. 畜牧与饲料科学, 2018,39(6):108-112.
[6]   Zhuang X T, Bai J, Zhang Z C . Application and Development of New Molecular Diagnostic Techniques in Animal Epidemics Detection. Animal Husbandry and Feed Science, 2018,39(6):108-112.
[7]   吴衍恒, 林金思, 师舞阳 , 等. 应用芯片式数字PCR检测人血清中登革病毒载量. 公共卫生与预防医学, 2019,30(03):16-20.
[7]   Wu Y H, Lin J S, Shi W Y , et al. Detection of dengue virus load in human serum by chip digital PCR. Pub Health and Prev Med, 2019,30(03):16-20.
[8]   BRAY E A . Classification of genes differentially expressed during water-deficit stree in Arabidopsis thaliana: An analysis using microarray and differential expression data. Annals of Botany, 2002,89:803-811.
[9]   郭柯磊, 欧阳昭连, 杜然然 , 等. 国际生物技术专利计量分析. 生物技术通讯, 2011,22(02):248-251.
[9]   Guo K L, Ouyang Z L, Du R R , et al. Study of International Patents on Biotechnology. Letters in Biotechnology 2011,22(02):248-251.
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