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Recent Progress on Fermentation and Antibacterial Applications of Surfactin |
MEI Yu-wei,YANG Zi-yun,YU Fan,LONG Xu-wei() |
Nanjing University of Science and Technology, Nanjing 210094,China |
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Abstract Surfactin is a kind of cyclic lipopeptide biosurfactant mainly synthesized by many Bacillus subtilis strains. Surfactin is well-accepted as one of the most powerful biosurfactants, presents excellent surface activities, can significantly reduce the surface tension force of water to below 27mN/m at a concentration of 10-30mg/L. In addition, surfactin has great biological activities like: anti-fungal, anti-virus, anti-tumor, insecticidal and anti-mycoplasma, and thus has of great applications potential in the fields of medicine, agriculture, food, cosmetics and petroleum industries. However, its real industrial applications were limited by the high production cost and lack of specific application yields. Many efforts have been done towards the improvement of surfactin production. The recent progresses on surfactin production, and its applications as an antibacterial agent have been reviewed.
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Received: 14 December 2019
Published: 02 June 2020
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Corresponding Authors:
Xu-wei LONG
E-mail: xuweilong@njust.edu.cn
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