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中国生物工程杂志

China Biotechnology
China Biotechnology
China Biotechnology  2020, Vol. 40 Issue (4): 91-96    DOI: 10.13523/j.cb.1910036
    
Research Progress of Photocrosslinked Hydrogel in Tissue Engineering
WANG Yuan-dou1,SU Feng1,2*,LI Su-ming3,*()
1 Institute of High Performance Polymers, Qingdao University of Science and Technology, Qingdao 266042, China
2 College of Chemical Engineering, Qingdao University of Science and Technology, Qingdao 266042, China
3 European Institute of Membranes, University of Montpellier, 34095 Montpellier Cedex, France
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Abstract  

Due to the biocompatibility, degradability, and similarity to the structure of natural extracellular matrix, hydrogel has become a research hotspot and focus of tissue engineering. Based on in-situ formation and injectability, and compatibility with existing processing technologies (3D printing, electrospinning), photocrosslinked hydrogels are widely used in the field of tissue engineering. In this paper, recent advances in the field of tissue engineering in photocrosslinked hydrogels are reviewed, including new advances in cartilage, bone, adipose and periodontal tissues. The paper reviews the photocrosslinked hydrogels and provides relevant references for future research.

Key words： Photocrosslinked hydrogel      Tissue engineering      Cell scaffold     
Received: 22 October 2019      Published: 18 May 2020
ZTFLH:  Q819  
Corresponding Authors: Su-ming LI     E-mail: lisuming@hotmail.com
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Yuan-dou WANG
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Cite this article:

WANG Yuan-dou,SU Feng,LI Su-ming. Research Progress of Photocrosslinked Hydrogel in Tissue Engineering. China Biotechnology, 2020, 40(4): 91-96.

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https://manu60.magtech.com.cn/biotech/10.13523/j.cb.1910036     OR     https://manu60.magtech.com.cn/biotech/Y2020/V40/I4/91

化学名称 缩写 光源 可聚合单体 文献
1-[4-(2-羟基乙氧基)苯基]-2-羟基-2-甲基-1-丙酮 Irgacure 2959 紫外光 GelMA, MCS, n-armPEG-PCL-AC, SMH, Col-GMA, HA-MA, CLF [16] 、[20] 、[25] 、[26] 、[34] 、[35] 、[36] 、[37] 、[49] 、[50]
苯基-2,4,6-三甲基苯甲酰基次膦酸锂 LAP 紫外光,可见光 PEG-PCL-DA, GelMA, GelNB, GelSH [18] 、[21] 、[31] 、[41] 、[42] 、[43]
2',4',5',7'-四溴荧光素二钠盐 曙红Y 可见光 GelMA, PEGDA, PEGNB [13] 、[14] 、[19]
2-羟基-2-甲基苯丙酮 Irgacure 1173 紫外光 MCS, PEGDA, DMA, GelMA [15] 、[47]
核黄素 维生素B2 可见光 F-HA, MA-CMCS [17]
Table 1 Types of widely used photoinitiators and light sources
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