| Orginal Article |
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| The Role of Exosomes in the Diagnosis and Treatment of Viral Infection |
MAO Hui,LV Yu-hua,ZHU Li-hui,LIN Yue-xia( ),LIAO Rong-rong() |
| Institute of Animal Husbandry and Veterinary Sciences, Shanghai Academy of Agricultural Sciences, Shanghai 201106, China |
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Abstract Exosomes are extracellular vesicles which released upon fusion of multivesicular bodies with the cytoplasmic membrane. Exosomes were shown to contain functional proteins, lipids, and nucleic acids derived from secretory cells that mediating cell-to-cell communications and hence playing important roles in the physiology of the healthy and diseased organism. At present, the investigation on the mechanism of action of exosomes in viral infection and the potential markers of exosomes as a diagnosis and treatment of viral infection are still in their infancy. First described the composition and biogenesis of exosomes, and then focused on the mechanism of action of exosomes in viral infection, especially its role in immune regulation, and finally explored the diagnoses of exomes as a viral infection. And the potential for therapeutic potential markers and their application prospects.
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Received: 22 May 2019
Published: 18 April 2020
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Corresponding Authors:
Yue-xia LIN,Rong-rong LIAO
E-mail: linyuexia@saas.sh.cn;lrrnd@163.com
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