研究报告 |
|
|
|
|
慢病毒载体介导GHRH基因在小鼠肌肉组织表达及对动物生长的影响 |
戴建威1,3, 章倩倩4, 刘松财3, 张明军3, 张永亮2 |
1. 广州医学院 广州 510182;
2. 华南农业大学动物科学学院 广州 510642;
3. 吉林大学畜牧兽医学院 长春 130062;
4. 中山大学生物工程中心 广州 510275 |
|
Lentiviral Vector Mediated GHRH Gene Expression in Mouse Muscle and the Effect on Growth of Animals |
DAI Jian-wei1,3, ZHANG Qian-qian4, LIU Song-cai3, ZHANG Ming-jun3, ZHANG Yong-liang2 |
1. Department of Biochemistry, Guangzhou Medical College, Guangzhou 510182, China;
2. College of Animal Science, South China Agricultural University, Guangzhou 510642, China;
3. Department of Biochemistry, Veterinary College, Jinlin University, Changchun 130062, China;
4. Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory for Biocontrol, Sun Yat-Sen University, Guangzhou 510275, China |
引用本文:
戴建威, 章倩倩, 刘松财, 张明军, 张永亮. 慢病毒载体介导GHRH基因在小鼠肌肉组织表达及对动物生长的影响[J]. 中国生物工程杂志, 2011, 31(7): 8-13.
DAI Jian-wei, ZHANG Qian-qian, LIU Song-cai, ZHANG Ming-jun, ZHANG Yong-liang. Lentiviral Vector Mediated GHRH Gene Expression in Mouse Muscle and the Effect on Growth of Animals. China Biotechnology, 2011, 31(7): 8-13.
链接本文:
https://manu60.magtech.com.cn/biotech/CN/
或
https://manu60.magtech.com.cn/biotech/CN/Y2011/V31/I7/8
|
[1] 张永亮,刘松财,欧阳红生,等.生长激素释放因子(GRF)在动物肌肉组织中的表达.中国兽医学报,2000,20(3):239-241. Zhang Y L, Liu S C, Ouyang H S, et al.Chinese Journal of Veterinary Science, 2000,20(3):239-241.
[2] Zhang Y L, Ren X H, Liu S C, et al. Overexpression of GRF encapsulated in PLGA microspheres in animal skeletal muscle induces body weight gain. Anim Biotechnol, 2007; 18(3): 163-175.
[3] 任晓慧,张永亮,刘松财,等.微球包裹pcDNA3-GHRH(1-32)在小鼠肌肉组织的表达及对生长的影响.生物工程学报,2004,20(4):615-618. Ren X H, Zhang Y L, Liu S C, et al.Chinese Journal of Biotechnology, 2004,20(4):615-618.
[4] 戴建威,刘松财,任晓慧,等.生长抑素与乙肝表面抗原真核表达载体构建及其对Vc獭兔生长的影响.中国兽医学报,2006,26(1):1-4. Dai J W, Liu S C, Ren X H, et al.Chinese Journal of Veterinary Science, 2006,26(1): 1-4.
[5] Dai J W,Liu S C,Zhang Y L. Simultaneous expression of Growth Hormone Releasing Hormone (GHRH) and Hepatitis B Surface Antigen/Somatostatin (HBsAg/SS) fusion genes in a construct in the skeletal muscle enhances rabbit weight gain. Animal Biotechnology, 2008, 19(2): 104-116.
[6] 周芬,程时远.基因治疗中的非病毒载体.化学通报, 2005, 68 (6):1-7. Zhou F, Cheng S Y. Chemistry, 2005,68 (6): 1-7.
[7] Naldini L,Blomer U,Gallay P,et al. In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector.Science,1996,272(5259):263-267.
[8] Blomer U,Naldini L,Kafri T,et al.Highly efficient and sustained gene transfer in adult neurons with a lentivirus vector.J Virol,1997,71(9):6641-6649.
[9] Kafri T,Blomer U,Peterson D A,et al.Sustained expression of genes delivered directly into liver and muscle by lentiviral vectors.Nat Genet,1997,17(3):314-317.
[10] 章倩倩,戴建威,张永亮,等.CMV与SP双启动子增强外源基因在小鼠骨骼肌中的表达效率. 中国生物化学与分子生物学报, 2007, 23(7): 554-559. Zhang Q Q, Dai J W, Zhang Y L. et al.Chinese Journal of Biochemistry and Molecular Biology, 2007, 23(7): 554-559.
[11] Sinn P L,Sauter S L,McCray P B Jr.Gene therapy progress and prospects:development of improved lentiviral and retroviral vectors--design,biosafety,and production.Gene Ther,2005,12(14):1089-1098.
[12] Beaudet M J,Rueda N, Kobinger G P, et al. Construction of a ganciclovir-sensitive lentiviral vector to assess the influence of angiopoietin-3 and soluble Tie2 on glioma growth. J Neurooncol, 2010,99(1): 1-11.
[13] Breckpot K, Escors D, Arce F, et al. HIV-1 lentiviral vector immunogenicity is mediated by Toll-like receptor 3 (TLR3) and TLR7. J Virol, 2010, 84(11): 5627-5636.
[14] Draghia-Akli R, Li X G, Schwatz R J.Enhanced growth by ectopic expression of growth Hormone releasing hormone using an injectable myogenic vector.Nature Biotechnology,1997,15:1285.
[15] Draghia-Akli R, Ellis K M.High-efficiency growth hormone releasing hormone plasmid vector administration into skeletal muscle mediated by electroporation in pigs. The FASEB Journal,2003,17(3):526-528.
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
|
Shared |
|
|
|
|
|
Discussed |
|
|
|
|