| 研究报告 |
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| 表达神经营养因子Neurturin的骨髓间充质干细胞的构建及体外活性检测 |
| 王晚璞, 孙茂盛, 李鸿钧, 谢天宏, 严敏, 周艳, 尹娜 |
| 北京协和医学院/中国医学科学院医学生物学研究所 昆明 650118 |
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| Establishment of Bone Marrow Mesenchymal Stem Cells Expressing Neurotrophic Factor Neurturin and Activity Detection in Vitro |
| WANG Wan-pu, SUN Mao-sheng, LI Hong-jun, XIE Tian-hong, YAN Min, ZHOU Yan, YIN Na |
| Laboratory of Biomolecular, Peking Union Medical College, Chinese Academy of Medical Sciences, Institute of Medical Biology, Kunming 650118, China |
引用本文:
王晚璞, 孙茂盛, 李鸿钧, 谢天宏, 严敏, 周艳, 尹娜. 表达神经营养因子Neurturin的骨髓间充质干细胞的构建及体外活性检测[J]. 中国生物工程杂志, 2012, 32(03): 1-6.
WANG Wan-pu, SUN Mao-sheng, LI Hong-jun, XIE Tian-hong, YAN Min, ZHOU Yan, YIN Na. Establishment of Bone Marrow Mesenchymal Stem Cells Expressing Neurotrophic Factor Neurturin and Activity Detection in Vitro. China Biotechnology, 2012, 32(03): 1-6.
链接本文:
https://manu60.magtech.com.cn/biotech/CN/
或
https://manu60.magtech.com.cn/biotech/CN/Y2012/V32/I03/1
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[1] Kotzbauer P T, Lampe P A, Heukeroth R O, et al. Neurturin, a relative of glial cell line derived neurotrophic factor. Nature, 1996, 384(6608):467-470.
[2] Kordower J H, Herzog C D, Biplob D, et al. Delivery of Neurturin by AAV2 (CERE-120)-Mediated Gene Transfer Provides Structural and Functional Neuroprotection and Neurorestoration in MPTP-Treated Monkeys. Ann Neurol, 2006,60(6):706-715.
[3] Pereira R, Halford K, O’ Hara M, et al. Cultured adherent cells from marrow can serve as long-lasting precursor cells for bone,cartilage, and lung in irradiated mice. Proc Natl Acad Sci USA,1995,92 (11):4857-4861.
[4] Prockop D. Marrow stromal cells as stem cells for nonhematopoietic tissues. Science, 1997,276 (5309):71-74.
[5] Pittenger M, Mackay A, Beck S C, et al. Multilineage potential of adult human mesenchymal stem cells. Science, 1999,284 (5411):143- 147.
[6] Richards M, Huibergtse B, Caplan A, et al. Marrow-derives progenitor cell injections enchance new bone formation during distraction. J Orthop Res,1999,17 (6):900-908.
[7] Li Y, Chen J, Wang L, et al. Intracerebral transplantation of bone marrow stromal cells in a 1-methyl-4-phenyl-1,2,3,6-tetrahdyropyridine mouse model of Parkinson’s disease. Neurosci Lett, 2001, 316 (2):67-70.
[8] Beal M. Experimental models of Parkinson’s disease. Nat Rev Neurosci, 2001,2(5):325-334.
[9] Liu S, Yu Y, An H, et al. Cloning and identification of a novel ubiquitin-like protein, BMSC-UbP from human bone marrow stromal cells. Immunol Lett, 2003, 86(2):169-175.
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