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中国生物工程杂志

CHINA BIOTECHNOLOGY
中国生物工程杂志  2011, Vol. 31 Issue (8): 133-138    
综述     
白斑综合征病毒囊膜蛋白在对虾免疫保护应用中的研究进展
冯书营, 景爱华, 杨建英
河南科技大学 医学技术与工程学院 洛阳 471003
Progress in the Researches on Immune-protection of WSSV Envelope Proteins to Shrimp
FENG Shu-ying, JING Ai-hua, YANG Jian-ying
College of Engineering and Medical Technology of Henan Science and Technology University,Luoyang 471003, China
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摘要:

白斑综合征自上世纪90年代初在水产养殖业中爆发以来,其病原体白斑综合征病毒的研究一直在深入开展,特别是WSSV结构蛋白的功能学研究尤为广泛,其主要方向集中在病毒囊膜蛋白对虾体的免疫保护上,并取得了显著的保护效果。从利用病毒囊膜蛋白作为亚单位疫苗免疫虾体、利用囊膜蛋白对应抗体保护虾体、构建囊膜蛋白基因核酸疫苗和利用RNAi干扰技术保护虾体等四个方面,对当前WSSV囊膜蛋白在对虾免疫保护中的应用进行了概述,并对其应用前景作一展望,旨在为及早开发出有效防治白斑综合征疾病的技术途径提供借鉴参考。

关键词: WSSV囊膜蛋白免疫保护研究进展    
Abstract:

White spot syndrome virus was deeply studied at all times since the white spot syndrome disease break out in shrimp culture from 1990’. The functional research of the WSSV structural proteins,especially the virus membrane proteins,and acquired the notable body protection for shrimp was mainly focused on. A comprehensive summary of the research progress of the WSSV membrane proteins,including utilized the membrane proteins as a subunit vaccine;utilized the corresponding antibodies of membrane proteins;constructed the nucleic acid vaccine;and utilized the RNAi technology for shrimp protection was given;and a view of the future application of WSSV membrane proteins in prevent of the white spot syndrome diseases was also provided.

Key words: WSSV    Membrane protein    Immune-protection    Research progress
收稿日期: 2011-02-28 出版日期: 2011-08-25
ZTFLH:  Q939.9  
基金资助:

国家自然科学基金资助项目(30900796)

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引用本文:

冯书营, 景爱华, 杨建英. 白斑综合征病毒囊膜蛋白在对虾免疫保护应用中的研究进展[J]. 中国生物工程杂志, 2011, 31(8): 133-138.

FENG Shu-ying, JING Ai-hua, YANG Jian-ying. Progress in the Researches on Immune-protection of WSSV Envelope Proteins to Shrimp. China Biotechnology, 2011, 31(8): 133-138.

链接本文:

https://manu60.magtech.com.cn/biotech/CN/        https://manu60.magtech.com.cn/biotech/CN/Y2011/V31/I8/133


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