| 综述 |
|
|
|
|
| 秀丽隐杆线虫先天免疫信号转导途径 |
| 王涛1,2, 杜丽1, 马琼1, 崔玉芳1 |
1. 军事医学科学院放射与辐射医学研究所 北京 100850;
2. 东南大学毫米波国家重点实验室 南京 210096 |
|
| Current Progress on the Signal Transduction Pathway of Innate Immunity in Caenorhabditis Elegans |
| WANG Tao1,2, DU Li1, MA Qiong1, CUI Yu-fang1 |
1. Beijing Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing 100850, China;
2. State Key Laboratory of Millimeter Wave, Southeast University, Nanjing 210096, China |
引用本文:
王涛, 杜丽, 马琼, 崔玉芳. 秀丽隐杆线虫先天免疫信号转导途径[J]. 中国生物工程杂志, 2011, 31(7): 121-125.
WANG Tao, DU Li, MA Qiong, CUI Yu-fang. Current Progress on the Signal Transduction Pathway of Innate Immunity in Caenorhabditis Elegans. China Biotechnology, 2011, 31(7): 121-125.
链接本文:
https://manu60.magtech.com.cn/biotech/CN/
或
https://manu60.magtech.com.cn/biotech/CN/Y2011/V31/I7/121
|
|
[1] Brenner S. The genetics of Caenorhabditis elegans. Genetics, 1974, 77(1):71-94.
[2] Couillauct C, Ewbank J J. Diverse bacteria are pathogens of C. elegans. Infect Immun, 2002, 70(8):4705-4707.
[3] Ewbank J J. Tackling both sides of the host-pathogen equation with Caenorhabditis elegans. Microbes Infect, 2002, 4(2):247-256.
[4] Kwon E S, Narasimhan S D, Yen K, et al. A new DAF-16 isoform regulates longevity. Nature, 2010, 466(7035):498-502.
[5] Kenyon C. The first long-lived mutants: discovery of the insulin/IGF-1 pathway for ageing. Phil Trans R Soc B, 2011, 366(1561):9-16.
[6] Evans E A, Chen W C, Tan M W. The DAF-2 insulin-like signaling pathway independently regulates aging and immunity in Caenorhabditis elegans. Aging Cell, 2008, 7(6):879-893.
[7] Williams T W, Dumas K J, Hu P J. EAK proteins: novel conserved regulation of Caenorhabditis elegans lifespan. Aging, 2010, 1(10):742-747.
[8] Jensen V L, Simonsen K T, Lee Y H, et al. RNAi screen of DAF-16/FOXO target genes in Caenorhabditis elegans links pathogenesis and dauer formation. PLOS ONE, 2010, 5(12):1-8.
[9] Murphy C T, McCarroll S A, Bargmann C I, et al. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature, 2003, 424(6946):277-283.
[10] Shivers R P,Youngman M J, Kim D H. Transcriptional responses to pathogens in Caenorhabditis elegans. Curr Opin Microbiol, 2008, 11(3):251-256.
[11] Yoko H, Masashi T, Shuji H. Redox regulation,gene expression and longevity. Geriatr Gerontol Int, 2010, 10(1):59-69.
[12] Chavez V, Mohri-Shiomi A, Maadani A, et al. Oxidative stress enzymes are required for DAF-16 mediated immunity due to generation of reactive oxygen species by Caenorhabditis elegans. Genetics, 2007, 176(3):1567-1577.
[13] Zugasti O, Eubank J J. Neuroimmune regulation of antimicrobial peptide xpression by a noncanonical TGF-βsignaling pathway in Caenorhabditis elegans epidermis. Nat Immunol, 2009, 10(3):249-256.
[14] Mallo G V, Kurz C L, Couillault C. Inducible antibacterial defense system in C. elegans. Curr Biol, 2002, 12(14):1209-1214.
[15] Roberts A F, Gumienny T L, Gleason R J. Regulation of genes affecting body size and innate immunity by the DBL-1/BMP-like pathway in Caenorhabditis elegans. BMC Dev Biol, 2010, 10(61):1-10.
[16] Kurz C L, Tan M W. Regulation of aging and innate immunity in Caenorhabditis elegans. Aging Cell, 2004, 3(4):185-193.
[17] Bolz D D,Tenor J L, Aballay A. A conserved PMK-1/P38 MAPK is required in Ceanorhabditis elegans tissue-specific immune response. J Biol Chem, 2010, 285(14):10832-10840.
[18] Mizuno T, Hisamoto N, Terada T, et al. The Caenorhabditis elegans MAPK phosphatase VHP-1 mediates a novel JNK-like signaling pathway in stress response. EMBO, 2004, 23(11):2226-2234.
[19] Nicholas H R, Hodgkin J. The ERK MAPK kinase cascade mediates tail swelling and a protective response to rectal infection in Caenorhabditis elegans. Curr Biol, 2004, 14(14):1256-1261.
[20] Kim D H, Liberati N T, Mizuno T, et al. Integration of Caenorhabditis elegans MAPK pathways mediating immunity and stress resistance by MEK-1 MAPK kinase and VHP-1 MAPK phosphatase. Proc Natl Acad Sci USA, 2004, 101(30):10990-10994.
[21] Gravato-Nobre M J, Hodgkin J. Caenorhabditis elegans as a model for innate immunity to pathogens. Cell Microbiol, 2005, 7(6):741-751.
[22] Putcha G V,Johnson E M. 'Men are but worms:’ neuronal cell death in C. elegnas and vertebrates. Cell Death Differ, 2004, 11(1):38-48.
[23] 王凯.生命科学研究中常用模式生物.生命科学研究, 2010,14(2):156-165. Wang K. Life Science Research, 2010, 14(2):156-165.
[24] Nehme R, Conradt B. Egl-1: a key activator of apoptotic cell death in C. elegans. Oncogene, 2008, 27(1):30-40.
[25] Aballay A, Ausubel F M. Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing. Proc Natl Acad Sci USA, 2001, 98(5):2735-2739.
[26] Tenor J L, Aballay A. A conserved Toll-like receptor is required for Caenorhabditis elegans innate immunity. Scientific Report, 2008, 9(1):103-109.
[27] Liberati N T, Fitzgeraldet K A, Kim D H, et al. Requirement for a conserved Toll/interleukin-1 resistance domain protein in the C.elegans immune response. Proc Natl Acad Sci USA, 2004, 101(17):6593-6598.
[28] Couillault C, Pujol N, Reboul J, et al. TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1,an ortholog of human SARM. Nat Immunol, 2004, 5(5):488-494.
[29] 杨再昌,杨小生. 秀丽隐杆线虫(Caenorhabditis elegans)在药物筛选中的应用.生命科学, 2009, 21(4):593-598. Yang Z C, Yang X S. Chinese Bulletion of Life Sciences, 2009, 21(4):593-598.
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
