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靶向融合蛋白XE-TNFαm2激活并清除潜伏于受感染细胞内的HIV的研 |
路金芝1,陈伟京1*,丁枫3*,佟薇2,李涛1,蒋虹2,杨晶3,丛喆2,魏强2,黄毅3,王憬惺3,卢圣栋1** |
1. 中国医学科学院基础医学研究所
2. 中国医学科学院输血研究所
3. 中国医学科学院实验动物研究所
4. 中国医学科学院中国协和医科大学基础医学研究所 |
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A targeting Fusion Protein XE-TNFαm2 Stimulates Latent HIV to Re-propagate and then Kills the Host Cells with un-mature HIV |
1.Institute of Basic Medical Sciences,Chinese Academy of Medical Sciences/Peking Union Medical College,Beijing 100005,China
2.Institute of Laboratory Animal Sciences,CAMS/PUMC, Beijing 100021,China
3.Institute of Blood Transfusion, CAMS, Chengdu 610081,China |
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[7] Brooks D G, Arlen P A, Gao L, et al.Identification of T cellsignaling pathways that stimulate latent HIV in primary cells. Proc Natl Acad Sci U S A,2003,100:1295512960.
[8] 路金芝,陈伟京,杨晶,等.靶向融合蛋白XETNFαm2 导致受HIV/SIV感染细胞的凋亡 中国生物工程杂志, 2009,29(3):913.Lu J Z,Chen W J,Yang J,et al.China Biotechology,2009,29(3):913. |
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