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阿维菌素衍生物CHC-B1的突变生物合成 |
姜薇1,汪洋2,张晓琳3,郭伟群2,刘娣4 |
1. 东北农业大学生命科学学院 哈尔滨 1500302
2. 国家粮食局科学研究院 北京 100037 |
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The Mutasynthetic Production of CHCB1 from a Streptomyces avermitilis Mutant in the Presence of Cyclohexanecarboxylic Acid |
JIANG Wei1,2, HONG Xiang2, ZHANG Xiao-Lin2, GUO Wei-Qun2, LIU Di1 |
1.College of Life Science,Northeast Agricultural University,Harbin150030,China
2.Academy of State Administration of Grain,Beijing100037,China |
引用本文:
姜薇,汪洋,张晓琳,郭伟群,刘娣. 阿维菌素衍生物CHC-B1的突变生物合成[J]. 中国生物工程杂志, 2009, 29(08): 68-74.
JIANG Wei, HONG Xiang, ZHANG Xiao-Lin, GUO Wei-Qun, LIU Di. The Mutasynthetic Production of CHCB1 from a Streptomyces avermitilis Mutant in the Presence of Cyclohexanecarboxylic Acid. China Biotechnology, 2009, 29(08): 68-74.
链接本文:
https://manu60.magtech.com.cn/biotech/CN/
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https://manu60.magtech.com.cn/biotech/CN/Y2009/V29/I08/68
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[1] 白宝星,张春燕,田敏,等.突变生物合成在微生物药物领域的研究进展.中国抗生素杂志,2007,32(2):65~73
Bai B X, Zhang CH Y, Tian M, et al.Chinese Journal of Antibiotics, 2007, 32(2):65~73
[2] 房春林,杨光有,古小彬.多拉菌素的研究进展.中国畜牧兽医,2006,33(5):55~57
Fang C L, Yang Y G, Gu X B, et al.China Animal Husbandry & Veterinary Medicine, 2006, 33(5):55~57
[3] Burg R W, Miller B M,Baker E E,et al.Avermectins,new family of potent anthelmintic agents:producing organism and fermentation.Antimicorb Agents Chemother,1979, 15 :361
[4] Claudio D D, Ronald W F, Edmund W H, et al. A second branchedchain alphaketo acid dehydrogenase gene cluster (bkdFGH) from Streptomyces avermitilis: its relationship to avermectin biosynthesis and construction of a bkdF mutant suitable for production of novel antiparasitic avermectins. J. Bacteriol,1995, 177: 3504~3511
[5] Cropp T A, Dennis J W, Reynolds K A. Identification of a cyclohexylcarbonyl CoA biosynthetic gene cluster and application in the production of doramectin. Nature, 2000, 18:980~983
[6] Hanahan D. Studies on transformation of Escherichia coli with plasmids. J Mot Biol,1983,166:557
[7] 郭伟群.阿维链霉菌高产菌株的选育和发酵条件的优化.北京:中国农业大学,2007
Guo W Q. Screening of high avermectinproducing strain and optimizes on the fermentation condition.Beijing: China Agricultural University, 2007
[8] Bierman M, Logan R, O'Brien K. Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp. Gene, 1992, 116:43~49
[9] Sambrook J, Fritsch E F, Maniatis T. Molecular Cloning. A Laboratory Manual.2nded. New York: Cold Spring Harbor laboratory Press, 1989
[10] MacNeil D J, Klapko L M. Transformation of Streptomyces avermitilis by plasmid DNA. J Ind Microbiol, 1987,2: 209~218
[11] Ikeda H, Kotaki H, Tanaka H, et al. Involvement of glucose catabolism in avermectin production by Streptomyces avermitilis. Antimicrob Agents Chemother, 1988,32:282~284
[12] Hopwood D A, Bibb M J, Chater K F, et al. Genetic manipulation of Streptomyces. A Laboratory Manual. Norwich: John Innes Foundation, 1985
[13] 宋渊,曹贵明,陈芝,等.阿维菌素高产菌株的选育及阿维菌素B1的鉴定.生物工程学报,2000,16(1):31~35
Song Y, Cao G M, Chen Z.Chinese Journal of Biotechnology,2000,16(1):31~35
[14] Christopher J D, Stephen P G, Alexander C G, et al. Novel avermectins produced by mutational biosynthesis. The Journal of Antibiotics, 1991,44:357~365 |
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