透明颤菌血红蛋白(Vitreoscilla Hemoglobin, VHb)是20世纪70年代后期发现的一种血红蛋白,该蛋白质能使透明颤菌在低氧的环境下生存,并保持较高的生长速率。随着其作用机理的深入研究,VHb在生物工程领域的应用越来越广泛。本文总结了近年来VHb的研究进展,包括蛋白结构、细胞定位、基因改组、作用机理等方面的研究,并概述了其在微生物发酵工业中的应用。
Vitreoscilla Hemoglobin (VHb) was discoved in the late 1970s, it is an element that can ensure Vitreoscilla survive and improve growth in an environment that contains insufficient amount of oxygen. Along with further mechanism research on VHb, this protein get more and more application on biotechnology fields. In this review we summary main results of research on VHb in recent years, including protein structure, intracellular localization, DNA shuffling and mechanisms of VHb function. Finally, we inllustuate the application of VHb on microorganism fermentation industry.
裴海生,杨光,李春,张刚,曹竹安. 透明颤菌血红蛋白的研究进展及其在发酵工业中的应用[J]. 中国生物工程杂志, 2008, 28(7): 133-138.
Chun Li . Development of Studies and Application in Fermentation of Vitreoscilla Hemoglobin. China Biotechnology, 2008, 28(7): 133-138.
https://manu60.magtech.com.cn/biotech/CN/ 或 https://manu60.magtech.com.cn/biotech/CN/Y2008/V28/I7/133
Cited