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中国生物工程杂志

CHINA BIOTECHNOLOGY
中国生物工程杂志
中国生物工程杂志  2024, Vol. 44 Issue (1): 61-71    DOI: 10.13523/j.cb.2311100
生物经济核心产业专题     
合成生物学与未来食品*
徐显皓,刘龙,陈坚**()
江南大学未来食品科学中心 无锡 214122
Synthetic Biology and Future Food
Xianhao XU,Long LIU,Jian CHEN**()
Science Center for Future Foods, Jiangnan University, Wuxi 214122, China
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摘要：

食品工业是保障国计民生的支柱产业。随着人口增长、环境污染、气候变化等问题的日益突出,亟需对传统的食品制造工艺进行转型升级。合成生物学的发展为食品制造工艺的变革提供了技术支持。合成生物学能够通过构建细胞工厂将可再生原料转化为重要的食品配料与组分,实现食品的绿色、高效、可持续生物制造。对未来食品制造相对于传统食品制造的特征与优势进行讨论,并列举合成生物学推动食品生物制造的前沿技术和代表性案例,最后对我国基于合成生物学的未来食品制造所面临的机遇与挑战进行展望。
关键词： 合成生物学;  未来食品;  细胞工厂;  人造肉;  人乳寡糖    
Abstract:

Food is a cornerstone industry for ensuring national prosperity and people’s well-being. However, with the increasing challenges posed by population growth, environmental pollution, and climate change, it is crucial to transform and upgrade traditional food manufacturing processes. The development of synthetic biology provides technological support for the revolution of food manufacturing processes. Synthetic biology can convert renewable raw materials into important food ingredients and components by constructing cell factories, enabling green, efficient, and sustainable bioproduction of food. This article discusses the characteristics and advantages of future food manufacturing compared to traditional methods, as well as the cutting-edge technologies and specific implementation cases driven by synthetic biology in food biomanufacturing. Finally, this review discusses the prospects and challenges facing China in the future food manufacturing based on synthetic biology.
Key words: Synthetic biology    Future food    Cell factories    Cultured meat    Human milk oligosaccharides
收稿日期: 2023-11-14 出版日期: 2024-02-04
ZTFLH:  Q819  
基金资助: *国家重点研发计划(2022YFC2104903);国家自然科学基金(32200050)
通讯作者: ** 电子信箱:jchen@jiangnan.edu.cn   
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徐显皓
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引用本文:

徐显皓, 刘龙, 陈坚. 合成生物学与未来食品*[J]. 中国生物工程杂志, 2024, 44(1): 61-71.

Xianhao XU, Long LIU, Jian CHEN. Synthetic Biology and Future Food. China Biotechnology, 2024, 44(1): 61-71.

链接本文:

https://manu60.magtech.com.cn/biotech/CN/10.13523/j.cb.2311100    或    https://manu60.magtech.com.cn/biotech/CN/Y2024/V44/I1/61

图1  基于合成生物学的未来食品制造
图2  基于合成生物学的细胞工厂构建流程
图3  乳蛋白的发酵合成工艺
图4  2'-FL的合成途径及常用改造策略
图5  7-DHC的合成途径及常用改造策略
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