生物支架材料——组织工程连载之二

doi:10.13523/j.cb.20140618

中国生物工程杂志

2014, Vol. 34

Issue (06): 122-127 DOI: 10.13523/j.cb.20140618

讲座

生物支架材料——组织工程连载之二

董茂盛¹, 王佃亮²

1. 第二炮兵总医院北京 100088;
2. 第二炮兵总医院药学部组织工程与再生医学实验室北京 100088

Biological Scaffold Materials

DONG Mao-sheng¹, WANG Dian-liang²

1. Department of General Surgery, The Second Artillery General Hospital, Beijing 100088, China;
2. Tissue Engineering and Regenerative Medicine Laboratory, Department of Pharmacy, The Second Artillery General Hospital, Beijing 100088, China

全文: PDF(465 KB) HTML

摘要：

具有三维结构的支架材料是组织工程的核心内容之一。现有组织工程支架可分为天然生物材料、合成有机材料和无机材料三类。支架材料近年来研究十分活跃，不仅在组织工程的最早产品人工皮肤领域进行了更为完善的研究和开发，同时在诸如人工骨、软骨、神经、血管、皮肤、肝、脾、肾、膀胱等方面进行了大量研究和探索。与普通组织工程支架需要预先制备并在体外成型不同，近年来在骨和软骨组织工程实践中兴起的可注射支架具有许多优势，是未来组织工程支架发展的重要方向之一。

关键词： 组织工程支架; 三维结构; 细胞外基质; 天然生物材料; 可注射支架

Abstract:

The scaffold material that have three-dimensional structure is another main content of tissue engineering. Current tissue engineering scaffolds are divided into three kinds including natural biomaterial, synthesized organic material and inorganic material. Scaffold material is a hot research topic in recent years, which is more perfectly studied and developed in the field of artificial skin that is the earliest tissue engineering product and made much investigation and exploration in other fields such as artificial bone, cartilage, nerve, blood vessel, skin, liver, spleen, kidney and bladder, etc. Unlike traditional tissue engineering scaffolds that need to be previously fabricated and shaped up in vitro, the injectable scaffolds that have grown up in bone and cartilage tissue engineering practices have many advantages, which is one of the important development direction of future tissue engineering scaffolds.

Key words: Tissue engineering scaffold Three-dimensional structure Extracelluar matrix Natural biomaterial Injectable scaffold

收稿日期: 2014-02-14 出版日期: 2014-06-25

ZTFLH:

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通讯作者: 王佃亮 E-mail: wangdianliang@sina.com

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引用本文:

董茂盛, 王佃亮. 生物支架材料——组织工程连载之二[J]. 中国生物工程杂志, 2014, 34(06): 122-127.

DONG Mao-sheng, WANG Dian-liang. Biological Scaffold Materials. China Biotechnology, 2014, 34(06): 122-127.

链接本文:

https://manu60.magtech.com.cn/biotech/CN/10.13523/j.cb.20140618 或 https://manu60.magtech.com.cn/biotech/CN/Y2014/V34/I06/122

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