Current Development of Intellectual Property Rights in Surface Plasmon Resonance Biosensor Technology

doi:10.13523/j.cb.2305013

China Biotechnology

2023, Vol. 43

Issue (11): 116-126 DOI: 10.13523/j.cb.2305013

Current Development of Intellectual Property Rights in Surface Plasmon Resonance Biosensor Technology

CHEN Yu-yang¹,LIU Jia-yuan²,HUANG Zi-qin²,CHEN Yu-bao³,XU Wen-juan^2,^**(

),LONG Feng²

1 China National Intellectual Property Administration, Beijing 100088, China
2 Renmin University of China, Beijing 100874, China
3 Institute of Laboratory Animal Sciences, Chinese Academy of Medical Sciences, Beijing 100021, China

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Abstract

Surface plasmon resonance (SPR) biosensors are a new type of biosensor technology based on the principle of SPR. They have numerous advantages including non-labeling, strong specificity, high sensitivity, and real-time dynamic detection, especially for the field of biological molecule interaction, drug-screening, etc. Many countries are stepping up their layout of intellectual property rights (IPRs) for SPR biosensor technology. The number of China’s intellectual property applications has increased significantly in recent years. Based on the IncoPat patent database, this study conducts an in-depth analysis on the overall development trend, intellectual property layout, popular technologies of SPR biosensors, and the identification of key IPRs. The results show that the SPR biosensor technology in China is becoming an increasingly active area of research, and China is ranked among the world’s leading countries in terms of the number of patent applications in this regard. However, several problems still exist, such as a small number of original IPRs, limited conversion rate of IPRs, and low market share of products. In view of the broad market prospects of SPR biosensor technologies, future development strategies of SPR biosensor technologies in China are proposed.

Key words： Surface plasmon resonance (SPR) Biosensor Patent analysis Intellectual property rights (IPRs)

Received: 10 May 2023 Published: 01 December 2023

ZTFLH:	Q81
	TP212.3

Corresponding Authors: Wen-juan XU E-mail: xuwenjuan@ruc.edu.cn

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	Yu-yang CHEN
	Jia-yuan LIU
	Zi-qin HUANG
	Yu-bao CHEN
	Wen-juan XU
	Feng LONG

Cite this article:

CHEN Yu-yang,LIU Jia-yuan,HUANG Zi-qin,CHEN Yu-bao,XU Wen-juan,LONG Feng. Current Development of Intellectual Property Rights in Surface Plasmon Resonance Biosensor Technology. China Biotechnology, 2023, 43(11): 116-126.

URL:

https://manu60.magtech.com.cn/biotech/10.13523/j.cb.2305013 OR https://manu60.magtech.com.cn/biotech/Y2023/V43/I11/116

Fig.1 Schematic diagram of SPR biosensor sensing principle

Fig.2 Annual application volume of SPR biosensor technology patents

Fig.3 Country ranking of global SPR biosensor technology patent applicants

Fig.4 Application for SPR biosensor technology patents in China

Fig.5 Patent applications for SPR biosensors in China by Chinese provinces

Table 1 Major global applicants for SPR biosensor technology patents

Table 2 Major applicants for SPR biosensor technology patents in China

Fig.6 Distribution of global SPR biosensor patent technology fields

Fig.7 Ranking of global SPR biosensor patent technology composition

Fig.8 Ranking of SPR biosensor patent applications in China

Fig.9 Keyword cloud extracted from the patent A. Fiber SPR biosensor B. Prism SPR biosensor C. Optical waveguide SPR biosensors D. Grating SPR biosensors E. LSPR biosensors F. SPR biosensors

Table 3 Core patents in the global SPR biosensor technology field (partial)

Table 4 Core patents in the field of SPR biosensor technology in China (partial)


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