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Research Progress on Biological Functions of miR-138 |
RAN Hong-biao,WANG Hui**(),ZHONG Jin-cheng**() |
Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Sichuan Province and Ministry of Education, Southwest Minzu University, Chengdu 610041, China |
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Abstract microRNAs(miRNAs)are highly conserved non-coding small RNA in eukaryotes. They have many biological functions and can participate in the regulation of disease, cell proliferation and differentiation and other biological process. miR-138 as a tumor suppressor has been widely studied in tumorigenesis and therapy and also plays a regulatory role in cardiovascular and neurological disorder processes, osteogenic differentiation, adipogenesis and ovarian function maintenance. In this paper, prospects for future research direction of miR-138 are analyzed and discussed on the basis of summarizing and analyzing the latest research progress of miR-138 related functions, aiming to provide reference and theoretical basis for exploring miR-138 biological functions in the future.
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Received: 05 October 2021
Published: 05 May 2022
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Corresponding Authors:
Hui WANG,Jin-cheng ZHONG
E-mail: wanghui892321@sina.cn;zhongjincheng518@126.com
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