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Domestic Research and Development Status of Antibody-drug Conjugates and Strategic Layout of Key Enterprises |
CHEN Wen-jie(),MIAO Xian-feng |
Hangzhou Firestone Technology Co. Ltd., Hangzhou 310051, China |
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Abstract Antibody-drug conjugates are immunoconjugates comprised of monoclonal antibodies tethered to a cytotoxic drug via a chemical linker.It has been proven to be a promising technical method in the clinical treatment of hematologic malignancies and solid tumors.Therefore,it has newly become one of the fastest growing areas in the researching and developing of anticancer drugs at home and overseas. Five key requirements of ADCs throughout the research and pharmacuetical manufacturing process were expatiated systematically,and the pipelines and strategic layout of major domestic companies were also analyzed in order to provide a reference for the R&D layout of ADCs for the emerging companies and industrial decision for regional government.
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Received: 14 May 2021
Published: 06 July 2021
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Corresponding Authors:
Wen-jie CHEN
E-mail: chenwj@hsmap.com
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