After testing the resistance 0f streptomycin to GX-29，the spores treated with UV light and microwave were regenerated on agar plants containing 18.2μg/mL streptomycin. A number of streptomycin resistant (str) mutants were obtained. Then we acquired a high antibiotic-producing strain L8 through re-screening by batch fermentation.The activity of the mutant L8 increased by 1.94 times over the original strain．The high productivity could be inherited after several subcultures.
Received: 03 March 2008
Published: 01 January 1900
