|
|
|
| Research Progress on miRNA Regulation of Myogenesis |
| TANG Zhi-xiong, GOU De-ming |
| College of Life Sciences, Shenzhen University, Shenzhen 518060, China |
|
|
|
Abstract Myogenesis involves myoblast proliferation and differentiation to myocytes, later,these myocytes fuse to form multinucleated myotubes. MicroRNAs (miRNAs) are small non-coding RNAs, which post-transcriptionally regulate gene expression by binding to the 3'UTR of target mRNA. miRNAs play important role in the regulation of myogenesis.The function of muscle-specific expression of miRNAs(myomiRs), such as miR-1, miR-133, miR-206, miR-208, miR-499 and miR-486, as well as several non-myomiRs, including miR-27, miR-29, miR-128, miR-199a and miR-431 were introduced. In addition, several lncRNAs those interact with miRNAs to regulate muscle differentiation have been summarized. The regulatory mechanism of miRNAs on myogenesis were elucidated and the latest research progress were reviewed.
|
|
Received: 12 April 2017
Published: 25 October 2017
|
|
|
|
|
| [1] |
Bartel D P. MicroRNAs:genomics, biogenesis, mechanism, and function. Cell, 2004, 116:281-297.
|
|
|
| [2] |
Orom U A, Nielsen F C, Lund a H. MicroRNA-10a binds the 5' UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell, 2008, 30:460-471.
|
|
|
| [3] |
Jopling C L, Yi M, Lancaster A M, et al. Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science, 2005, 309:1577-1581.
|
|
|
| [4] |
Forman J J, Legesse-Miller A, Coller H A. A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proceedings of the National Academy of Sciences of the United States of America, 2008, 105:14879-14884.
|
|
|
| [5] |
O'rourke J R, Georges S A, Seay H R, et al. Essential role for Dicer during skeletal muscle development. Developmental Biology, 2007, 311:359-368.
|
|
|
| [6] |
Endo T. Molecular mechanisms of skeletal muscle development, regeneration, and osteogenic conversion. Bone, 2015, 80:2-13.
|
|
|
| [7] |
Brand-Saberi B. Genetic and epigenetic control of skeletal muscle development. Annals of anatomy=Anatomischer Anzeiger:official organ of the Anatomische Gesellschaft, 2005, 187:199-207.
|
|
|
| [8] |
Ito Y, Kayama T, Asahara H. A systems approach and skeletal myogenesis. Comparative and Functional Genomics, 2012, 2012:7594-7507.
|
|
|
| [9] |
Hinterberger T J, Sassoon D A, Rhodes S J, et al. Expression of the muscle regulatory factor MRF4 during somite and skeletal myofiber development. Developmental Biology, 1991, 147:144-156.
|
|
|
| [10] |
Buckingham M, Relaix F. The role of Pax genes in the development of tissues and organs:Pax3 and Pax7 regulate muscle progenitor cell functions. Annual Review of Cell and Developmental Biology, 2007, 23:645-673.
|
|
|
| [11] |
Edmondson D G, Cheng T C, Cserjesi P, et al. Analysis of the myogenin promoter reveals an indirect pathway for positive autoregulation mediated by the muscle-specific enhancer factor MEF-2. Molecular and Cellular Biology, 1992, 12:3665-3677.
|
|
|
| [12] |
Vignaud A, Hourde C, Butler-Browne G, et al. Differential recovery of neuromuscular function after nerve/muscle injury induced by crude venom from Notechis scutatus, cardiotoxin from Naja atra and bupivacaine treatments in mice. Neuroscience Research, 2007, 58:317-323.
|
|
|
| [13] |
Van Rooij E, Sutherland L B, Qi X, et al. Control of stress-dependent cardiac growth and gene expression by a microRNA. Science, 2007, 316:575-579.
|
|
|
| [14] |
Sempere L F, Freemantle S, Pitha-Rowe I, et al. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biology, 2004, 5:R13.
|
|
|
| [15] |
Wang X H. MicroRNA in myogenesis and muscle atrophy. Current Opinion in Clinical Nutrition and Metabolic Care, 2013, 16:258-266.
|
|
|
| [16] |
Duan C, Ren H, Gao S. Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins:roles in skeletal muscle growth and differentiation. General and Comparative Endocrinology, 2010, 167:344-351.
|
|
|
| [17] |
Elia L, Contu R, Quintavalle M, et al. Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions. Circulation, 2009, 120:2377-2385.
|
|
|
| [18] |
Kozakowska M, Ciesla M, Stefanska A, et al. Heme oxygenase-1 inhibits myoblast differentiation by targeting myomirs. Antioxidants & Redox Signaling, 2012, 16:113-127.
|
|
|
| [19] |
Sato M M, Nashimoto M, Katagiri T, et al. Bone morphogenetic protein-2 down-regulates miR-206 expression by blocking its maturation process. Biochemical and Biophysical Research Communications, 2009, 383:125-129.
|
|
|
| [20] |
King I N, Yartseva V, Salas D, et al. The RNA-binding protein TDP-43 selectively disrupts microRNA-1/206 incorporation into the RNA-induced silencing complex. The Journal of Biological Chemistry, 2014, 289:14263-14271.
|
|
|
| [21] |
Lu L, Zhou L, Chen E Z, et al. A novel YY1-miR-1 regulatory circuit in skeletal myogenesis revealed by genome-wide prediction of YY1-miRNA network. PloS One, 2012, 7:e27596.
|
|
|
| [22] |
Chen J F, Mandel E M, Thomson J M, et al. The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nature Genetics, 2006, 38:228-233.
|
|
|
| [23] |
Wilson-Rawls J, Molkentin J D, Black B L, et al. Activated notch inhibits myogenic activity of the MADS-Box transcription factor myocyte enhancer factor 2C. Molecular and Cellular Biology, 1999, 19:2853-2862.
|
|
|
| [24] |
Gagan J, Dey B K, Layer R, et al. Notch3 and Mef2c proteins are mutually antagonistic via Mkp1 protein and miR-1/206 microRNAs in differentiating myoblasts. The Journal of Biological Chemistry, 2012, 287:40360-40370.
|
|
|
| [25] |
Chen J F, Tao Y, Li J, et al. microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7. The Journal of Cell Biology, 2010, 190:867-879.
|
|
|
| [26] |
Dey B K, Gagan J, Dutta A. miR-206 and miR-486 induce myoblast differentiation by downregulating Pax7. Molecular and Cellular Biology, 2011, 31:203-214.
|
|
|
| [27] |
Goljanek-Whysall K, Sweetman D, Abu-Elmagd M, et al. MicroRNA regulation of the paired-box transcription factor Pax3 confers robustness to developmental timing of myogenesis. Proceedings of the National Academy of Sciences of the United States of America, 2011, 108:11936-11941.
|
|
|
| [28] |
Kim H K, Lee Y S, Sivaprasad U, et al. Muscle-specific microRNA miR-206 promotes muscle differentiation. The Journal of Cell Biology, 2006, 174:677-687.
|
|
|
| [29] |
Alteri A, De Vito F, Messina G, et al. Cyclin D1 is a major target of miR-206 in cell differentiation and transformation. Cell Cycle, 2013, 12:3781-3790.
|
|
|
| [30] |
Li L, Sarver A L, Alamgir S, et al. Downregulation of microRNAs miR-1, -206 and -29 stabilizes PAX3 and CCND2 expression in rhabdomyosarcoma. Laboratory Investigation; A Journal of Technical Methods and Pathology, 2012, 92:571-583.
|
|
|
| [31] |
Jash S, Dhar G, Ghosh U, et al. Role of the mTORC1 complex in satellite cell activation by RNA-induced mitochondrial restoration:dual control of cyclin D1 through microRNAs. Molecular and Cellular Biology, 2014, 34:3594-3606.
|
|
|
| [32] |
Kukreti H, Amuthavalli K, Harikumar A, et al. Muscle-specific microRNA1(miR1) targets heat shock protein 70(HSP70) during dexamethasone-mediated atrophy. The Journal of Biological Chemistry, 2013, 288:6663-6678.
|
|
|
| [33] |
James P L, Stewart C E, Rotwein P. Insulin-like growth factor binding protein-5 modulates muscle differentiation through an insulin-like growth factor-dependent mechanism. The Journal of Cell Biology, 1996, 133:683-693.
|
|
|
| [34] |
Liu N, Williams A H, Maxeiner J M, et al. microRNA-206 promotes skeletal muscle regeneration and delays progression of Duchenne muscular dystrophy in mice. The Journal of Clinical Investigation, 2012, 122:2054-2065.
|
|
|
| [35] |
Yan B, Zhu C D, Guo J T, et al. miR-206 regulates the growth of the teleost tilapia (Oreochromis niloticus) through the modulation of IGF-1 gene expression. The Journal of Experimental Biology, 2013, 216:1265-1269.
|
|
|
| [36] |
Sun Y, Ge Y, Drnevich J, et al. Mammalian target of rapamycin regulates miRNA-1 and follistatin in skeletal myogenesis. The Journal of Cell Biology, 2010, 189:1157-1169.
|
|
|
| [37] |
Kalderon N, Epstein M L, Gilula N B. Cell-to-cell communication and myogenesis. The Journal of Cell Biology, 1977, 75:788-806.
|
|
|
| [38] |
Anderson C, Catoe H, Werner R. MIR-206 regulates connexin43 expression during skeletal muscle development. Nucleic Acids Research, 2006, 34:5863-5871.
|
|
|
| [39] |
Rosenberg M I, Georges S A, Asawachaicharn A, et al. MyoD inhibits Fstl1 and Utrn expression by inducing transcription of miR-206. The Journal of Cell Biology, 2006, 175:77-85.
|
|
|
| [40] |
Sharma M, Juvvuna P K, Kukreti H, et al. Mega roles of microRNAs in regulation of skeletal muscle health and disease. Frontiers in Physiology, 2014, 5:239.
|
|
|
| [41] |
Jeng S F, Rau C S, Liliang P C, et al. Profiling muscle-specific microRNA expression after peripheral denervation and reinnervation in a rat model. Journal of Neurotrauma, 2009, 26:2345-2353.
|
|
|
| [42] |
Taulli R, Bersani F, Foglizzo V, et al. The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation. The Journal of Clinical Investigation, 2009, 119:2366-2378.
|
|
|
| [43] |
Luo Y Q, Wu X X, Ling Z X, et al. microRNA133a targets Foxl2 and promotes differentiation of C2C12 into myogenic progenitor cells. DNA and Cell Biology, 2015, 34:29-36.
|
|
|
| [44] |
Liu N, Bezprozvannaya S, Shelton J M, et al. Mice lacking microRNA 133a develop dynamin 2-dependent centronuclear myopathy. The Journal of Clinical Investigation, 2011, 121:3258-3268.
|
|
|
| [45] |
Chen X, Wang K H, Chen J N, et al. In vitro evidence suggests that miR-133a-mediated regulation of uncoupling protein 2(UCP2) is an indispensable step in myogenic differentiation. Journal of Biological Chemistry, 2009, 284:5362-5369.
|
|
|
| [46] |
Zhang Y, Xie R L, Gordon J, et al. Control of mesenchymal lineage progression by microRNAs targeting skeletal gene regulators Trps1 and Runx2. The Journal of Biological Chemistry, 2012, 287:21926-21935.
|
|
|
| [47] |
Yin H, Pasut A, Soleimani V D, et al. MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16. Cell Metabolism, 2013, 17:210-224.
|
|
|
| [48] |
Zhang D, Li X, Chen C, et al. Attenuation of p38-mediated miR-1/133 expression facilitates myoblast proliferation during the early stage of muscle regeneration. PloS One, 2012, 7:e41478.
|
|
|
| [49] |
Nakasa T, Ishikawa M, Shi M, et al. Acceleration of muscle regeneration by local injection of muscle-specific microRNAs in rat skeletal muscle injury model. Journal of Cellular and Nolecular Medicine, 2010, 14:2495-2505.
|
|
|
| [50] |
Van Rooij E, Quiat D, Johnson B A, et al. A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Developmental Cell, 2009, 17:662-673.
|
|
|
| [51] |
Van Rooij E, Liu N, Olson E N. MicroRNAs flex their muscles. Trends Genet, 2008, 24:159-166.
|
|
|
| [52] |
Callis T E, Pandya K, Seok H Y, et al. MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. Journal of Clinical Investigation, 2009, 119:2772-2786.
|
|
|
| [53] |
Bell M L, Buvoli M, Leinwand L A. Uncoupling of expression of an intronic MicroRNA and its myosin host gene by exon skipping. Molecular and Cellular Biology, 2010, 30:1937-1945.
|
|
|
| [54] |
Small E M, O'rourke J R, Moresi V, et al. Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486. Proceedings of the National Academy of Sciences of the United States of America, 2010, 107:4218-4223.
|
|
|
| [55] |
Garza-Rodea A S, Baldwin D M, Oskouian B, et al. Sphingosine phosphate lyase regulates myogenic differentiation via S1P receptor-mediated effects on myogenic microRNA expression. FASEB Journal:official publication of the Federation of American Societies for Experimental Biology, 2014, 28:506-519.
|
|
|
| [56] |
Alexander M S, Casar J C, Motohashi N, et al. Regulation of DMD pathology by an ankyrin-encoded miRNA. Skeletal Muscle, 2011, 1:27.
|
|
|
| [57] |
Alexander M S, Casar J C, Motohashi N, et al. MicroRNA-486-dependent modulation of DOCK3/PTEN/AKT signaling pathways improves muscular dystrophy-associated symptoms. The Journal of Clinical Investigation, 2014, 124:2651-2667.
|
|
|
| [58] |
Huang Z, Chen X, Yu B, et al. MicroRNA-27a promotes myoblast proliferation by targeting myostatin. Biochemical and Biophysical Research Communications, 2012, 423:265-269.
|
|
|
| [59] |
Mcfarlane C, Vajjala A, Arigela H, et al. Negative auto-regulation of myostatin expression is mediated by Smad3 and microRNA-27. PloS One, 2014, 9:e87687.
|
|
|
| [60] |
Crist C G, Montarras D, Pallafacchina G, et al. Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression. Proceedings of the National Academy of Sciences of the United States of America, 2009, 106:13383-13387.
|
|
|
| [61] |
Wei W, He H B, Zhang W Y, et al. miR-29 targets Akt3 to reduce proliferation and facilitate differentiation of myoblasts in skeletal muscle development. Cell Death & Disease, 2013, 4:e668.
|
|
|
| [62] |
Wang H, Garzon R, Sun H, et al. NF-kappaB-YY1-miR-29 regulatory circuitry in skeletal myogenesis and rhabdomyosarcoma. Cancer Cell, 2008, 14:369-381.
|
|
|
| [63] |
Wang X H, Hu Z, Klein J D, et al. Decreased miR-29 suppresses myogenesis in CKD. Journal of the American Society of Nephrology:JASN, 2011, 22:2068-2076.
|
|
|
| [64] |
Winbanks C E, Wang B, Beyer C, et al. TGF-beta regulates miR-206 and miR-29 to control myogenic differentiation through regulation of HDAC4. The Journal of Biological Chemistry, 2011, 286:13805-13814.
|
|
|
| [65] |
Zhou L, Wang L, Lu L, et al. Inhibition of miR-29 by TGF-beta-Smad3 signaling through dual mechanisms promotes transdifferentiation of mouse myoblasts into myofibroblasts. PloS One, 2012, 7:e33766.
|
|
|
| [66] |
Zhou L, Wang L, Lu L, et al. A novel target of microRNA-29, Ring1 and YY1-binding protein (Rybp), negatively regulates skeletal myogenesis. The Journal of Biological Chemistry, 2012, 287:25255-25265.
|
|
|
| [67] |
Motohashi N, Alexander M S, Shimizu-Motohashi Y, et al. Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis. Journal of Cell Science, 2013, 126:2678-2691.
|
|
|
| [68] |
Dai Y, Zhang W R, Wang Y M, et al. MicroRNA-128 regulates the proliferation and differentiation of bovine skeletal muscle satellite cells by repressing Sp1. Molecular and Cellular Biochemistry, 2016, 414:37-46.
|
|
|
| [69] |
Shi L, Zhou B, Li P, et al. MicroRNA-128 targets myostatin at coding domain sequence to regulate myoblasts in skeletal muscle development. Cellular Signalling, 2015, 27:1895-1904.
|
|
|
| [70] |
Alexander M S, Kawahara G, Motohashi N, et al. MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation. Cell Death and Differentiation, 2013, 20:1194-1208.
|
|
|
| [71] |
Jia L, Li Y F, Wu G F, et al. MiRNA-199a-3p regulates C2C12 myoblast differentiation through IGF-1/AKT/mTOR signal pathway. International Journal of Molecular Sciences, 2013, 15:296-308.
|
|
|
| [72] |
Wu R, Li H, Zhai L, et al. MicroRNA-431 accelerates muscle regeneration and ameliorates muscular dystrophy by targeting Pax7 in mice. Nature Communications, 2015, 6:7713.
|
|
|
| [73] |
Lee K P, Shin Y J, Panda a C, et al. miR-431 promotes differentiation and regeneration of old skeletal muscle by targeting Smad4. Genes & Development, 2015, 29:1605-1617.
|
|
|
| [74] |
Lu L, Sun K, Chen X, et al. Genome-wide survey by ChIP-seq reveals YY1 regulation of lincRNAs in skeletal myogenesis. Embo J, 2013, 32:2575-2588.
|
|
|
| [75] |
Dey B K, Pfeifer K, Dutta A. The H19 long noncoding RNA gives rise to microRNAs miR-675-3p and miR-675-5p to promote skeletal muscle differentiation and regeneration. Genes & Development, 2014, 28:491-501.
|
|
|
| [76] |
Wang Y, Pang W J, Wei N, et al. Identification, stability and expression of Sirt1 antisense long non-coding RNA. Gene, 2014, 539:117-124.
|
|
|
| [77] |
Cesana M, Cacchiarelli D, Legnini I, et al. A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell, 2011, 147:358-369.
|
|
|
| [78] |
Legnini I, Morlando M, Mangiavacchi A, et al. A feedforward regulatory loop between HuR and the long noncoding RNA linc-MD1 controls early phases of myogenesis. Mol Cell, 2014, 53:506-514.
|
|
|
| [79] |
Wang G Q, Wang Y, Xiong Y, et al. Sirt1 AS lncRNA interacts with its mRNA to inhibit muscle formation by attenuating function of miR-34a. Scientific Reports, 2016, 6:218-265.
|
|
|
| [80] |
Qiu H, Liu N, Luo L, et al. MicroRNA-17-92 regulates myoblast proliferation and differentiation by targeting the ENH1/Id1 signaling axis. Cell Death and Differentiation, 2016, 23:1658-1669.
|
|
|
| [81] |
Qiu H, Zhong J, Luo L, et al. Regulatory Axis of miR-195/497 and HMGA1-Id3 governs muscle cell proliferation and differentiation. International Journal of Biological Sciences, 2017, 13:157-166.
|
|
|
|
Viewed |
|
|
|
Full text
|
|
|
|
|
Abstract
|
|
|
|
|
Cited |
|
|
|
|
| |
Shared |
|
|
|
|
| |
Discussed |
|
|
|
|
