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Seed Cells |
WANG Dian-liang |
Tissue Engineering and Regenerative Medicine Laboratory, Department of Pharmacy, The Second Artillery General Hospital, Beijing 100088, China |
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Abstract Seed cell is another main research content of tissue engineering. To obtain enough quantity and quality of seed cell is necessary for research and application of tissue engineering. The seed cells for tissue engineering must have an ability of developing new tissue structure, which are mainly autologous, allogeneic and heterogenou and have different advantages and disadvantages when using. Some adult stem cells including hematopoietic stem cell, bone marrow stem cell, neural stem cell, adipose-derived stem cell and skin stem cell are important seed cells for no ethic disputes and relatively simple developing differentiation conditions, etc. Human embryonic stem cell and its tissue engineering still need a long way to go if they are applied in clinical medicine. Other cells can also be used as tissue engineering seed cells, including endothelial cells, epithelial cells, fibroblast cells, bone cells, osteoblast cells, horn cells, preadipose cells, adipose cells, tendon cells, etc. These cells are differentiated and have a limited ability of division but still applied in tissue engineering. Ideal seed cells have certain standards.
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Received: 19 June 2014
Published: 25 July 2014
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