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中国生物工程杂志

China Biotechnology
China Biotechnology  2015, Vol. 35 Issue (10): 108-114    DOI: 10.13523/j.cb.20151016
    
Antibiotic Resistances in Environmental Microbiota and Antibiotic Resistome
TIAN Bao-yu, MA Rong-qin
Engineering Research Center of Industrial Microbiology , Ministry of Education, Fujian Normal University; College of Life Sciences, Fuzhou 350108, China
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Abstract  

Extensive uses of antibiotics have resulted in rapid growing resistance and emergence of resistant bacterial pathogens in medical availability and clinical practice. Resistance to a variety of antibiotics in microbial pathogens is currently considered as one of the most challenging problems in public health care. However, recent studies find that the resistant pathogenic microorganisms mainly obtain antibiotics resistance genes by lateral gene transferring than mutagenesis as assumed before. Recent development in ecology and evolutionary biology of the environmental resistome, and the origin, evolution and the crossing dissemination of the resistant genes among the pathogenic bacteria and the environmental microbiome were reviewed. And also, the application of the high-through sequencing and metagenomics in the research of the environmental resistome were discussed.



Key wordsEnvironmental microbiota      Resistome      Metagenomics      Antibiotic resistance     
Received: 19 May 2015      Published: 25 October 2015
ZTFLH:  Q939.92  
Cite this article:

TIAN Bao-yu, MA Rong-qin. Antibiotic Resistances in Environmental Microbiota and Antibiotic Resistome. China Biotechnology, 2015, 35(10): 108-114.

URL:

http://manu60.magtech.com.cn/biotech/10.13523/j.cb.20151016     OR     http://manu60.magtech.com.cn/biotech/Y2015/V35/I10/108

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