| [1] Heir S, Nerhus T K, Rtterud J H, et al. Focal cartilage defects in the knee impair quality of life as much as severe osteoarthritis: a comparison of knee injury and osteoarthritis outcome score in 4 patient categories scheduled for knee surgery.Am J Sports Med, 2010,382:231-237.
[2] Bentley G, Biant L C, Vijayan S,et al. Minimum ten-year results of a prospective randomized study of autologous chondrocyte implantation versus mosaicplasty for symptomatic articular cartilage lesions of the knee. J Bone Joint Surg Br, 2012,94:504-509.
[3] Brittberg M, Lindahl A, Nilsson A, et al.Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation. N Engl J Med, 1994,331:889-895.
[4] Augello A L, Kurth T B, De Bari C.Mesenchymal stem cells: a perspective from in vitro cultures to in vivo migration and niches.Eur Cell Mater,2010,20:121-133.
[5] Gardner O F, Alini M, Stoddart M J. Mesenchymal stem cells derived from human bone marrow.Methods Mol Biol, 2015,1340:41-52.
[6] Yoon B S, Lyons K M.Multiple functions of BMPs in chondrogenesis.J CellBiochem,2004,93(1):93-103.
[7] Liao J, Hu N, Zhou N, et al. Sox9 potentiates BMP2-induced chondrogenic differentiation and inhibits BMP2-induced osteogenic differentiation.PLoS One, 2014,9(2):e89025.
[8] Valcourt U, Ronzière M C, Winkler P, et al. Differenteffects of bone morphogenetic proteins 2, 4, 12, and 13 on the expression of cartilage and bone markers in the MC615 chondrocyte cell line, 1999,251(2):264-274.
[9] Drissi M H , Li X , Sheu T J ,et al. Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes.J Cell Biochem, 2003,90 (6): 1287-1298.
[10] Mahmoudifar N, Doran P M. Chondrogenesis and cartilage tissue engineering: the longer road to technology development. Trends Biotechnol,2012,30(3):166-176.
[11] Falah M, Nierenberg G, Soudry M, et al. Treatment of articular cartilage lesions of the knee. Int Orthop,2010,34(5):621-630.
[12] Chen S Y, Fu P R, Cong R S, et al. Strategies to minimize hypertrophy in cartilage engineering and regeneration.Genes Dis,2015,2(1):76-95.
[13] Tse W T, Pendleton J D, Beyer W M,et al.Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantation.Transplantation,2003,75(3):389-397.
[14] Nishimura R, Hata K, Matsubara T, et al. Regulation of bone and cartilage development by network between BMP signalling and transcription factors. J Biochem,2012,151( 3) : 247-254.
[15] Hennig T, Lorenz H, Thiel A, et al. Reduced chondrogenic potential of adipose tissue derived stromal cells correlates with an altered TGFbeta receptor and BMP profile and is overcome by BMP-6. J Cell Physiol, 2007,211(3):682-691.
[16] Studer D, Millan C, Ozturk E,et al. Molecular and biophysical mechanisms regulating hypertrophic differentiation in chondrocytes and mesenchymal stem cells.Eur Cell Mater,2012,24:118-135.
[17] Swingler T E, Wheeler G, Carmont V, et al. The expression and function of microRNAs in chondrogenesis and osteoarthritis. Arthritis Rheum,2012,64:1909-1919.
[18] Chen H, Ghori-Javed F Y, Rashid H, et al.Runx2 regulates endochondral ossification through control of chondrocyte proliferation and differentiation. J Bone Miner Res,2014,29(12):2653-2665.
[19] Choi J Y, Pratap J, Javed A, et al.Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development. Proc Natl Acad Sci USA, 2001,98(15):8650-8655.
[20] Takarada T, Hinoi E, Nakazato R,et al.An analysis of skeletal development in osteoblasts pecific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice. J Bone Miner Res,2013,28(10):2064-2069.
[21] Zhang Z, Hou C, Meng F, et al.MiR-455-3p regulates early chondrogenic differentiation via inhibiting Runx2.FEBS Lett,2015,589(23):3671-3678. |
