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| Application of OMICS Technology in Construction of Saccharomyces cerevisiae Strains for Ethanol Production |
| LI Yun-cheng, TANG Yue-qin, KIDA Kenji |
1. College of Light Industry, Textile and Food Engineering, Sichuan University, Chengdu 610065, China;
2. College of Architecture and Environment, Sichuan University, Chengdu 610207, China |
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Abstract Bioethanol is considered as the most important alternative of fossil fuel. Saccharomyces cerevisiae is the most effective ethanol-producing microorganism widely used in the current bioethanol industry. It is very important and urgent to construct strains with excellent inhibitor tolerance and pentose fermenting ability for the production of bioethanol from lignocellulosic biomass. Since the OMICS technologies, including genomics, proteomics, transcriptomics, metabolomics and fluxomics, can reveal the laws of life activities of strains in different level from genotype to phenotype, it has been broadly applied in construction of engineered strains, especially in the identification of target genes, the optimization of metabolic pathway and the reveal of metabolic mechanism. The application of OMICS makes strain construction works more targeted and clarity, and the breeding cycle is greatly shortened.The application and recent progress of OMICS in construction of Saccharomyces cerevisia strains for bioethanol production are discussed.
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Received: 17 October 2013
Published: 25 February 2014
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