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Structure and function of snake venom secretory phospholipase A2 |
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Abstract Secretory phospholipase A2 (sPLA2) is an important component of snake venom which has a variety of biological activities. They exert their different functions by molecular and structural diversity, eventually triggering kinds of physiological and patho-physiological effects. This review summarized the structure and biological activities of snake venom sPLA2 with emphasizing its relationship between diverse pharmacological effects and structures. In addition, some mechanisms of sPLA2 actions and hot research field of sPLA2 were also discussed.
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Received: 25 March 2008
Published: 01 January 1900
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