中国生物工程杂志

Antihypertensive peptides (AHPs) have good effect of decreasing blood pressure, also have low adverse effects and toxicity. Now it has been received great interests in gene engineering. This paper briefly reviewed the necessity of construction gene-engineering strain which expressing AHPs and other small peptides. Discussed the strategys and theoretical foundation of chosen peptides, construction tandem repeats, chosen expression vectors during the gene engineering constructions, mainly introduced the advantages and disadvantages of different types of expressing vectors. The purpose of this paper is to providing a reference for the future construction gene-engineering strain which expressing AHPs and conveniencing the design of this kind of experiment.