Abstract Aldehyde groups were produced on silica surface through silanisation and Terephthal-dicarboxaldehyde self-assembly. Antibody was immobilized on silica surface through condensation reaction between an amine and an aldehyde. Activity of antibody was investigated through antigen-antibody reaction. Experiment show antibody can be attached on silica surface though this way and its activity is retentive. This method can be used in protein detection and protein chip.
Received: 21 February 2006
Published: 25 June 2006
