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中国生物工程杂志

China Biotechnology
China Biotechnology  2010, Vol. 30 Issue (06): 122-129    DOI: Q819
    
Pre-clinical Application and Perspective of Ribozyme and DNAzyme
ZHOU Ying,MAO Jian-ping
Beijing Institute of Radiation Medicine, Beijing 100850,China
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Abstract  

Ribozymes and DNAzymes have a function of hydrolysis to mRNA molecules. They have become important tools for blocking gene expression and anti-virus. In recent years, Ribozymes and DNAzymes have been used in inclinical studies, and there have got many successful examples. This revew compares their differences and characteristics between Ribozyme and DNAzyme, and summarise the progress in anti-virus, anti-cancer, treatment of genetic diseases, treatment of nervous system diseases in pre-clinical researches. It was supposed to give a prospective remarks.



Key wordsRibozyme      DNAzyme      Gene therapy     
Received: 24 March 2010      Published: 12 June 2010
Cite this article:

ZHOU Ying, MAO Jian-Beng. Pre-clinical Application and Perspective of Ribozyme and DNAzyme. China Biotechnology, 2010, 30(06): 122-129.

URL:

https://manu60.magtech.com.cn/biotech/Q819     OR     https://manu60.magtech.com.cn/biotech/Y2010/V30/I06/122

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